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| 28.05.2022 | 13:00 | Blau-Weiß 90 Berlin | - | Torgelower FC Greif | 0:2 (0:2) | |
| 29.05.2022 | 14:00 | 1. FC Lok Stendal | - | MSV Pampow | 1:3 (0:3) | |
| 14:00 | Brandenburger SC Süd | - | Victoria Seelow | 1:2 (0:0) | ||
| 14:00 | CFC Hertha 06 | - | Hertha Zehlendorf | 1:3 (0:0) | ||
| 14:00 | FC Mecklenburg Schwerin | - | SC Staaken | 1:5 (0:3) | ||
| 14:00 | Greifswalder FC | - | Ludwigsfelder FC | 1:0 (0:0) | ||
| 14:00 | Hansa Rostock II | - | MSV 1919 Neuruppin | 3:3 (2:2) | ||
| 14:00 | Rostocker FC | - | SFC Stern 1900 | 3:0 (2:0) | ||
| 14:00 | TSG Neustrelitz | - | RSV Eintracht 1949 | 3:0 (1:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | ∅ | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Greifswalder FC | 28 | 19 | 5 | 4 | 52:26 | 26 | 62 | 2.21 |
| 2 |
|
Hertha Zehlendorf | 29 | 20 | 3 | 6 | 62:25 | 37 | 63 | 2.17 |
| 3 |
|
Blau-Weiß 90 Berlin | 28 | 18 | 2 | 8 | 59:36 | 23 | 56 | 2.00 |
| 4 |
|
CFC Hertha 06 | 29 | 17 | 6 | 6 | 50:32 | 18 | 57 | 1.97 |
| 5 |
|
Rostocker FC | 28 | 17 | 2 | 9 | 66:25 | 41 | 53 | 1.89 |
| 6 |
|
TSG Neustrelitz | 28 | 15 | 7 | 6 | 41:24 | 17 | 52 | 1.86 |
| 7 |
|
SC Staaken | 29 | 14 | 8 | 7 | 54:32 | 22 | 50 | 1.72 |
| 8 |
|
Torgelower FC Greif | 28 | 13 | 6 | 9 | 56:32 | 24 | 45 | 1.61 |
| 9 |
|
Eintracht Mahlsdorf | 28 | 13 | 6 | 9 | 46:33 | 13 | 45 | 1.61 |
| 10 |
|
RSV Eintracht 1949 | 29 | 10 | 12 | 7 | 44:37 | 7 | 42 | 1.45 |
| 11 |
|
Hansa Rostock II | 28 | 10 | 8 | 10 | 60:48 | 12 | 38 | 1.36 |
| 12 |
|
MSV Pampow | 28 | 9 | 7 | 12 | 42:52 | -10 | 34 | 1.21 |
| 13 |
|
FC Mecklenburg Schwerin | 29 | 10 | 4 | 15 | 38:55 | -17 | 34 | 1.17 |
| 14 |
|
Ludwigsfelder FC | 29 | 9 | 6 | 14 | 31:44 | -13 | 33 | 1.14 |
| 15 |
|
MSV 1919 Neuruppin | 28 | 5 | 9 | 14 | 31:60 | -29 | 24 | 0.86 |
| 16 |
|
Brandenburger SC Süd | 29 | 4 | 7 | 18 | 22:48 | -26 | 19 | 0.66 |
| 17 |
|
SFC Stern 1900 | 28 | 3 | 8 | 17 | 28:60 | -32 | 17 | 0.61 |
| 18 |
|
Victoria Seelow | 29 | 4 | 4 | 21 | 30:79 | -49 | 16 | 0.55 |
| 19 |
|
1. FC Lok Stendal | 28 | 3 | 4 | 21 | 25:89 | -64 | 13 | 0.46 |
| Promotion | |
| Relégation | |
| Relégation |
