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| 27.03.1981 | 20:00 | FC Schalke 04 | - | SV Bayer 04 Leverkusen | 3:1 (1:1) | |
| 20:00 | Bayer 05 Uerdingen | - | VfL Bochum | 1:0 (0:0) | ||
| 28.03.1981 | 15:30 | Bayern München | - | TSV 1860 München | 1:1 (0:0) | |
| 15:30 | Borussia Dortmund | - | Hamburger SV | 6:2 (2:2) | ||
| 15:30 | Fortuna Düsseldorf | - | VfB Stuttgart | 3:1 (1:1) | ||
| 15:30 | 1. FC Köln | - | 1. FC Kaiserslautern | 2:2 (1:1) | ||
| 15:30 | Eintracht Frankfurt | - | 1. FC Nürnberg | 3:0 (2:0) | ||
| 15:30 | Bor. Mönchengladbach | - | MSV Duisburg | 4:1 (1:1) | ||
| 15:30 | Arminia Bielefeld | - | Karlsruher SC | 4:1 (1:0) |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Hamburger SV | 26 | 17 | 5 | 4 | 60:33 | 27 | 39:13 |
| 2 |
|
Bayern München | 26 | 14 | 9 | 3 | 59:36 | 23 | 37:15 |
| 3 |
|
1. FC Kaiserslautern | 26 | 12 | 9 | 5 | 48:30 | 18 | 33:19 |
| 4 |
|
VfB Stuttgart | 26 | 13 | 7 | 6 | 52:37 | 15 | 33:19 |
| 5 |
|
Eintracht Frankfurt | 26 | 12 | 8 | 6 | 48:37 | 11 | 32:20 |
| 6 |
|
1. FC Köln | 26 | 10 | 8 | 8 | 45:39 | 6 | 28:24 |
| 7 |
|
Borussia Dortmund | 26 | 10 | 7 | 9 | 58:48 | 10 | 27:25 |
| 8 |
|
VfL Bochum | 26 | 6 | 14 | 6 | 39:33 | 6 | 26:26 |
| 9 |
|
Bor. Mönchengladbach | 26 | 10 | 6 | 10 | 47:50 | -3 | 26:26 |
| 10 |
|
Karlsruher SC | 26 | 7 | 11 | 8 | 38:46 | -8 | 25:27 |
| 11 |
|
Fortuna Düsseldorf | 26 | 8 | 7 | 11 | 48:51 | -3 | 23:29 |
| 12 |
|
SV Bayer 04 Leverkusen | 26 | 6 | 9 | 11 | 38:45 | -7 | 21:31 |
| 13 |
|
MSV Duisburg | 26 | 6 | 9 | 11 | 30:41 | -11 | 21:31 |
| 14 |
|
TSV 1860 München | 26 | 7 | 6 | 13 | 39:51 | -12 | 20:32 |
| 15 |
|
1. FC Nürnberg | 26 | 8 | 4 | 14 | 37:49 | -12 | 20:32 |
| 16 |
|
FC Schalke 04 | 26 | 7 | 6 | 13 | 37:65 | -28 | 20:32 |
| 17 |
|
Bayer 05 Uerdingen | 26 | 7 | 5 | 14 | 37:53 | -16 | 19:33 |
| 18 |
|
Arminia Bielefeld | 26 | 6 | 6 | 14 | 37:53 | -16 | 18:34 |
