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|
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| 04.12.2021 | 11:00 | FC Ingolstadt 04 | - | Eintracht Frankfurt | 1:1 (0:0) | |
| 14:30 | FC Augsburg | - | 1. FC Kaiserslautern | 4:1 (1:1) | ||
| 05.12.2021 | 11:00 | SpVgg Unterhaching | - | SV Wehen Wiesbaden | 3:1 (1:0) | |
| 11:00 | Bayern München | - | TSV 1860 München | 1:2 (1:0) | ||
| 12:00 | 1. FSV Mainz 05 | - | SV 07 Elversberg | 4:0 (0:0) | ||
| 13:00 | FSV Frankfurt | - | Karlsruher SC | 3:2 (0:0) | ||
| 13:00 | SpVgg Greuther Fürth | - | SV Darmstadt 98 | 2:1 (1:1) | ||
| 14:00 | SSV Reutlingen | - | SC Freiburg | 0:4 (0:3) | ||
| 12.02.2022 | 13:00 | 1. FC Nürnberg | - | 1899 Hoffenheim | 1:3 (1:1) | |
| 23.02.2022 | 19:00 | Stuttgarter Kickers | - | 1. FC Heidenheim 1846 | 0:2 (0:1) |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
VfB Stuttgart | 12 | 11 | 1 | 0 | 44:12 | 32 | 34 |
| 2 |
|
SpVgg Unterhaching | 13 | 11 | 0 | 2 | 35:17 | 18 | 33 |
| 3 |
|
1. FSV Mainz 05 | 13 | 9 | 3 | 1 | 40:13 | 27 | 30 |
| 4 |
|
SC Freiburg | 13 | 9 | 1 | 3 | 39:18 | 21 | 28 |
| 5 |
|
1899 Hoffenheim | 12 | 9 | 0 | 3 | 36:19 | 17 | 27 |
| 6 |
|
FC Augsburg | 12 | 8 | 0 | 4 | 28:19 | 9 | 24 |
| 7 |
|
Bayern München | 12 | 7 | 1 | 4 | 32:16 | 16 | 22 |
| 8 |
|
SpVgg Greuther Fürth | 12 | 6 | 2 | 4 | 17:15 | 2 | 20 |
| 9 |
|
1. FC Nürnberg | 13 | 6 | 1 | 6 | 32:24 | 8 | 19 |
| 10 |
|
FSV Frankfurt | 13 | 5 | 2 | 6 | 17:19 | -2 | 17 |
| 11 |
|
TSV 1860 München | 12 | 5 | 1 | 6 | 13:16 | -3 | 16 |
| 12 |
|
Stuttgarter Kickers | 12 | 5 | 1 | 6 | 21:26 | -5 | 16 |
| 13 |
|
1. FC Heidenheim 1846 | 12 | 4 | 3 | 5 | 25:33 | -8 | 15 |
| 14 |
|
SV Darmstadt 98 | 13 | 5 | 0 | 8 | 18:31 | -13 | 15 |
| 15 |
|
Eintracht Frankfurt | 13 | 3 | 4 | 6 | 17:24 | -7 | 13 |
| 16 |
|
Karlsruher SC | 12 | 3 | 2 | 7 | 16:20 | -4 | 11 |
| 17 |
|
1. FC Kaiserslautern | 13 | 3 | 2 | 8 | 27:33 | -6 | 11 |
| 18 |
|
SV Wehen Wiesbaden | 12 | 2 | 1 | 9 | 13:34 | -21 | 7 |
| 19 |
|
FC Ingolstadt 04 | 12 | 1 | 4 | 7 | 11:34 | -23 | 7 |
| 20 |
|
SV 07 Elversberg | 12 | 2 | 1 | 9 | 8:34 | -26 | 7 |
| 21 |
|
SSV Reutlingen | 12 | 0 | 2 | 10 | 9:41 | -32 | 2 |
| Play-off | |
| Relégation |
