 |
 |
|
|
| H (Match allé) | Uberlândia - MG | - | Aparecidense - GO | 0:1 (0:0) | ||
| R (match retour) | Aparecidense - GO | - | Uberlândia - MG | 1:1 (0:0) | ||
| H (Match allé): 09.10.2021 20:00 | R (match retour): 16.10.2021 20:00 | vainqueur: Aparecidense - GO | ||||
| H (Match allé) | América - RN | - | Campinense - PB | 0:0 (0:0) | ||
| R (match retour) | Campinense - PB | - | América - RN | 4:2 (0:0, 0:0) tab | ||
| H (Match allé): 09.10.2021 22:30 | R (match retour): 16.10.2021 22:30 | vainqueur: Campinense - PB | ||||
| H (Match allé) | Atlético Cearense - CE | - | Ferroviária - SP | 1:1 (1:1) | ||
| R (match retour) | Ferroviária - SP | - | Atlético Cearense - CE | 3:4 (0:0, 0:0, 0:0) tab | ||
| H (Match allé): 10.10.2021 20:00 | R (match retour): 17.10.2021 20:00 | vainqueur: Atlético Cearense - CE | ||||
| H (Match allé) | S.E.R. Caxias - RS | - | ABC - RN | 0:0 (0:0) | ||
| R (match retour) | ABC - RN | - | S.E.R. Caxias - RS | 3:0 (0:0) | ||
| H (Match allé): 10.10.2021 22:30 | R (match retour): 17.10.2021 22:30 | vainqueur: ABC - RN | ||||
