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| 24.07.2022 | 16:00 | Belgrano de San Francisco | - | Crucero del Norte | 1:0 (1:0) | |
| 20:00 | Douglas Haig | - | Atlético Paraná | 1:2 (0:1) | ||
| 20:00 | Sarmiento de Resistencia | - | Sportivo Las Parejas | 1:1 (0:1) | ||
| 20:30 | Defensores Belgrano (VR) | - | Gimnasia y Tiro de Salta | 0:1 (0:0) | ||
| 20:30 | Gimnasia y Esgrima (CdU) | - | Boca Unidos | 1:0 (1:0) | ||
| 21:00 | San Martín de Formosa | - | Defensores de Pronunciamiento | 2:0 (2:0) | ||
| 22:00 | Racing de Córdoba | - | Juventud Antoniana | 2:1 (1:1) | ||
| 26.07.2022 | 03:00 | Central Norte | - | Unión de Sunchales | 3:2 (0:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Racing de Córdoba | 20 | 12 | 7 | 1 | 35:10 | 25 | 43 |
| 2 |
|
Sarmiento de Resistencia | 20 | 10 | 8 | 2 | 26:10 | 16 | 38 |
| 3 |
|
Central Norte | 19 | 10 | 8 | 1 | 29:14 | 15 | 38 |
| 4 |
|
Douglas Haig | 20 | 9 | 5 | 6 | 31:19 | 12 | 32 |
| 5 |
|
San Martín de Formosa | 19 | 9 | 5 | 5 | 31:21 | 10 | 32 |
| 6 |
|
Gimnasia y Esgrima (CdU) | 20 | 9 | 5 | 6 | 22:19 | 3 | 32 |
| 7 |
|
Gimnasia y Tiro de Salta | 20 | 9 | 4 | 7 | 19:20 | -1 | 31 |
| 8 |
|
Sportivo Las Parejas | 20 | 8 | 6 | 6 | 23:19 | 4 | 30 |
| 9 |
|
Belgrano de San Francisco | 20 | 8 | 4 | 8 | 26:22 | 4 | 28 |
| 10 |
|
Crucero del Norte | 20 | 7 | 6 | 7 | 17:23 | -6 | 27 |
| 11 |
|
Juventud Antoniana | 20 | 6 | 5 | 9 | 15:24 | -9 | 23 |
| 12 |
|
Boca Unidos | 19 | 4 | 8 | 7 | 15:19 | -4 | 20 |
| 13 |
|
Defensores Belgrano (VR) | 20 | 5 | 3 | 12 | 17:25 | -8 | 18 |
| 14 |
|
Unión de Sunchales | 20 | 5 | 3 | 12 | 21:33 | -12 | 18 |
| 15 |
|
Atlético Paraná | 20 | 3 | 7 | 10 | 17:31 | -14 | 16 |
| 16 |
|
Defensores de Pronunciamiento | 20 | 3 | 7 | 10 | 12:29 | -17 | 16 |
| 17 |
|
Juventud Unida de Gualeguaychú | 19 | 4 | 3 | 12 | 16:34 | -18 | 15 |
| Play-off |
