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| 04.06.2022 | 20:30 | Crucero del Norte | - | Gimnasia y Tiro de Salta | 2:1 (1:1) | |
| 05.06.2022 | 16:00 | Juventud Antoniana | - | Unión de Sunchales | 1:2 (1:0) | |
| 16:00 | Juventud Unida de Gualeguaychú | - | San Martín de Formosa | 1:0 (1:0) | ||
| 16:00 | Sportivo Las Parejas | - | Atlético Paraná | 0:0 (0:0) | ||
| 16:15 | Boca Unidos | - | Defensores de Pronunciamiento | 0:0 (0:0) | ||
| 16:30 | Belgrano de San Francisco | - | Douglas Haig | 0:0 (0:0) | ||
| 22:30 | Gimnasia y Esgrima (CdU) | - | Central Norte | 0:0 (0:0) | ||
| 22:30 | Racing de Córdoba | - | Defensores Belgrano (VR) | 2:1 (0:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Racing de Córdoba | 11 | 7 | 4 | 0 | 19:3 | 16 | 25 |
| 2 |
|
Central Norte | 11 | 6 | 5 | 0 | 15:5 | 10 | 23 |
| 3 |
|
Crucero del Norte | 12 | 6 | 4 | 2 | 15:13 | 2 | 22 |
| 4 |
|
Douglas Haig | 12 | 6 | 2 | 4 | 17:9 | 8 | 20 |
| 5 |
|
Sarmiento de Resistencia | 11 | 5 | 5 | 1 | 11:3 | 8 | 20 |
| 6 |
|
San Martín de Formosa | 11 | 5 | 3 | 3 | 14:8 | 6 | 18 |
| 7 |
|
Sportivo Las Parejas | 12 | 5 | 3 | 4 | 14:13 | 1 | 18 |
| 8 |
|
Boca Unidos | 11 | 3 | 5 | 3 | 9:12 | -3 | 14 |
| 9 |
|
Gimnasia y Tiro de Salta | 11 | 4 | 2 | 5 | 7:11 | -4 | 14 |
| 10 |
|
Gimnasia y Esgrima (CdU) | 11 | 3 | 4 | 4 | 9:11 | -2 | 13 |
| 11 |
|
Defensores Belgrano (VR) | 12 | 3 | 3 | 6 | 13:14 | -1 | 12 |
| 12 |
|
Unión de Sunchales | 11 | 3 | 3 | 5 | 10:14 | -4 | 12 |
| 13 |
|
Belgrano de San Francisco | 11 | 3 | 3 | 5 | 8:12 | -4 | 12 |
| 14 |
|
Defensores de Pronunciamiento | 11 | 3 | 3 | 5 | 7:11 | -4 | 12 |
| 15 |
|
Juventud Antoniana | 12 | 3 | 3 | 6 | 6:14 | -8 | 12 |
| 16 |
|
Atlético Paraná | 11 | 1 | 4 | 6 | 5:13 | -8 | 7 |
| 17 |
|
Juventud Unida de Gualeguaychú | 11 | 2 | 0 | 9 | 7:20 | -13 | 6 |
| Play-off |
