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| 26.08.2022 | 23:00 | Central Córdoba SdE | - | Lanús | 2:2 (1:2) | |
| 27.08.2022 | 02:00 | Arsenal de Sarandí | - | Huracán | 1:1 (0:0) | |
| 18:00 | San Lorenzo | - | Rosario Central | 1:1 (0:0) | ||
| 20:30 | Banfield | - | Defensa y Justicia | 1:2 (0:2) | ||
| 20:30 | Newell's Old Boys | - | Godoy Cruz | 1:2 (1:1) | ||
| 23:00 | Argentinos Juniors | - | Platense | 0:2 (0:1) | ||
| 23:00 | Talleres de Córdoba | - | Racing Club | 1:1 (0:1) | ||
| 28.08.2022 | 01:30 | Tigre | - | River Plate | 1:1 (0:1) | |
| 18:00 | Barracas Central | - | Colón de Santa Fe | 1:0 (1:0) | ||
| 18:00 | Sarmiento de Junín | - | Gimnasia de La Plata | 0:0 (0:0) | ||
| 20:30 | Independiente | - | Vélez Sarsfield | 1:1 (1:0) | ||
| 23:00 | Boca Juniors | - | Atlético Tucumán | 2:1 (0:1) | ||
| 29.08.2022 | 01:30 | Estudiantes | - | Patronato de Paraná | 1:0 (1:0) | |
| 01:30 | Unión de Santa Fe | - | Aldosivi | 0:0 (0:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Atlético Tucumán | 16 | 9 | 5 | 2 | 19:8 | 11 | 32 |
| 2 |
|
Gimnasia de La Plata | 16 | 8 | 6 | 2 | 16:7 | 9 | 30 |
| 3 |
|
Huracán | 16 | 7 | 7 | 2 | 19:12 | 7 | 28 |
| 4 |
|
Godoy Cruz | 16 | 8 | 4 | 4 | 20:14 | 6 | 28 |
| 5 |
|
Argentinos Juniors | 16 | 8 | 3 | 5 | 18:14 | 4 | 27 |
| 6 |
|
River Plate | 16 | 7 | 5 | 4 | 25:14 | 11 | 26 |
| 7 |
|
Boca Juniors | 16 | 8 | 2 | 6 | 21:21 | 0 | 26 |
| 8 |
|
Racing Club | 16 | 6 | 7 | 3 | 23:14 | 9 | 25 |
| 9 |
|
Platense | 16 | 6 | 7 | 3 | 17:13 | 4 | 25 |
| 10 |
|
San Lorenzo | 16 | 5 | 9 | 2 | 22:17 | 5 | 24 |
| 11 |
|
Patronato de Paraná | 16 | 6 | 5 | 5 | 22:19 | 3 | 23 |
| 12 |
|
Unión de Santa Fe | 16 | 6 | 5 | 5 | 22:24 | -2 | 23 |
| 13 |
|
Estudiantes | 16 | 6 | 4 | 6 | 16:17 | -1 | 22 |
| 14 |
|
Newell's Old Boys | 16 | 5 | 5 | 6 | 14:16 | -2 | 20 |
| 15 |
|
Barracas Central | 16 | 5 | 5 | 6 | 18:24 | -6 | 20 |
| 16 |
|
Tigre | 16 | 4 | 7 | 5 | 22:21 | 1 | 19 |
| 17 |
|
Arsenal de Sarandí | 16 | 3 | 10 | 3 | 16:17 | -1 | 19 |
| 18 |
|
Sarmiento de Junín | 16 | 5 | 4 | 7 | 16:20 | -4 | 19 |
| 19 |
|
Rosario Central | 16 | 5 | 4 | 7 | 12:16 | -4 | 19 |
| 20 |
|
Banfield | 16 | 4 | 6 | 6 | 15:17 | -2 | 18 |
| 21 |
|
Central Córdoba SdE | 16 | 5 | 3 | 8 | 19:23 | -4 | 18 |
| 22 |
|
Defensa y Justicia | 16 | 4 | 6 | 6 | 14:18 | -4 | 18 |
| 23 |
|
Colón de Santa Fe | 16 | 4 | 6 | 6 | 13:18 | -5 | 18 |
| 24 |
|
Talleres de Córdoba | 16 | 3 | 7 | 6 | 14:17 | -3 | 16 |
| 25 |
|
Independiente | 16 | 3 | 6 | 7 | 15:19 | -4 | 15 |
| 26 |
|
Aldosivi | 16 | 3 | 4 | 9 | 10:23 | -13 | 13 |
| 27 |
|
Vélez Sarsfield | 16 | 1 | 9 | 6 | 17:22 | -5 | 12 |
| 28 |
|
Lanús | 16 | 2 | 5 | 9 | 14:24 | -10 | 11 |
