| 1. Journée | 13.08.2011 | Defensor Sporting | - | Rampla Juniors | 2:0 | ||||
| 2. Journée | 20.08.2011 | Nacional | - | Defensor Sporting | 2:2 |  |
|||
| 3. Journée | 28.08.2011 | Defensor Sporting | - | Cerrito | 1:1 | ||||
| 4. Journée | 03.09.2011 | Peñarol | - | Defensor Sporting | 1:0 | ||||
| 5. Journée | 11.09.2011 | Defensor Sporting | - | Fénix | 0:1 | ||||
| 6. Journée | 18.09.2011 | Liverpool | - | Defensor Sporting | 2:3 | ||||
| 7. Journée | 24.09.2011 | Defensor Sporting | - | Rentistas | 1:0 | |
|||
| 8. Journée | 02.10.2011 | Racing | - | Defensor Sporting | 0:3 | ||||
| 9. Journée | 09.10.2011 | Defensor Sporting | - | CA Cerro | 2:3 |  |
|
||
| 10. Journée | 08.11.2011 | Montevideo Wanderers | - | Defensor Sporting | 0:2 | ||||
| 12. Journée | 13.11.2011 | Cerro Largo | - | Defensor Sporting | 0:3 | ||||
| 13. Journée | 19.11.2011 | Defensor Sporting | - | Bella Vista | 2:1 | ||||
| 14. Journée | 27.11.2011 | El Tanque Sisley | - | Defensor Sporting | 2:2 | ||||
| 15. Journée | 02.12.2011 | Defensor Sporting | - | River Plate | 0:2 | |
Uruguay
Italie