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| 23.10.2021 | 12:00 | Somaspor | - | Kahramanmaraşspor | 2:0 (1:0) | |
| 13:00 | Adıyamanspor | - | Diyarbekirspor | 1:2 (0:1) | ||
| 13:00 | Bodrumspor | - | Bayburt İl Özel İdare | 1:2 (0:0) | ||
| 13:00 | Hekimoğlu Trabzon | - | Turgutluspor | 2:2 (1:1) | ||
| 13:00 | Inegölspor | - | Sakaryaspor | 0:5 (0:1) | ||
| 13:00 | Niğde Anadolu FK | - | Ergene Velimeşe | 1:2 (1:1) | ||
| 13:00 | Vanspor FK | - | Sivas Belediyespor | 0:3 (0:1) | ||
| 18:00 | Afjet Afyonspor | - | Etimesgut Belediyespor | 1:1 (0:1) | ||
| 18:00 | Ankaraspor | - | Serik Belediyespor | 3:2 (2:1) | ||
| 18:00 | Çorum FK | - | Sarıyer SK | 5:0 (1:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Sivas Belediyespor | 9 | 6 | 3 | 0 | 17:1 | 16 | 21 |
| 2 |
|
Vanspor FK | 9 | 6 | 2 | 1 | 17:9 | 8 | 20 |
| 3 |
|
Hekimoğlu Trabzon | 9 | 5 | 4 | 0 | 17:6 | 11 | 19 |
| 4 |
|
Çorum FK | 9 | 5 | 3 | 1 | 15:4 | 11 | 18 |
| 5 |
|
Ankaraspor | 9 | 5 | 2 | 2 | 22:11 | 11 | 17 |
| 6 |
|
Sakaryaspor | 9 | 4 | 5 | 0 | 13:2 | 11 | 17 |
| 7 |
|
Bayburt İl Özel İdare | 9 | 5 | 2 | 2 | 11:8 | 3 | 17 |
| 8 |
|
Bodrumspor | 9 | 5 | 1 | 3 | 16:6 | 10 | 16 |
| 9 |
|
Afjet Afyonspor | 9 | 3 | 5 | 1 | 15:12 | 3 | 14 |
| 10 |
|
Somaspor | 9 | 4 | 2 | 3 | 13:11 | 2 | 14 |
| 11 |
|
Etimesgut Belediyespor | 9 | 4 | 2 | 3 | 12:12 | 0 | 14 |
| 12 |
|
Serik Belediyespor | 9 | 4 | 0 | 5 | 10:14 | -4 | 12 |
| 13 |
|
Inegölspor | 9 | 3 | 2 | 4 | 13:17 | -4 | 11 |
| 14 |
|
Diyarbekirspor | 9 | 3 | 1 | 5 | 10:11 | -1 | 10 |
| 15 |
|
Sarıyer SK | 9 | 3 | 1 | 5 | 10:16 | -6 | 10 |
| 16 |
|
Ergene Velimeşe | 9 | 2 | 1 | 6 | 7:21 | -14 | 7 |
| 17 |
|
Turgutluspor | 9 | 1 | 3 | 5 | 11:18 | -7 | 6 |
| 18 |
|
Niğde Anadolu FK | 9 | 1 | 1 | 7 | 4:22 | -18 | 4 |
| 19 |
|
Adıyamanspor | 9 | 1 | 0 | 8 | 8:18 | -10 | 3 |
| 20 |
|
Kahramanmaraşspor | 9 | 0 | 0 | 9 | 3:25 | -22 | 0 |
| Promotion | |
| Play-off | |
| Relégation |
