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| 05.02.2022 | 11:00 | Adıyamanspor | - | Inegölspor | 2:0 (1:0) | |
| 11:00 | Ergene Velimeşe | - | Somaspor | 1:2 (0:1) | ||
| 11:00 | Etimesgut Belediyespor | - | Niğde Anadolu FK | 3:2 (2:2) | ||
| 06.02.2022 | 11:00 | Afjet Afyonspor | - | 1461 Trabzon FK | 0:1 (0:0) | |
| 11:00 | Diyarbekirspor | - | Ankaraspor | 1:0 (1:0) | ||
| 11:00 | Kahramanmaraşspor | - | Sarıyer SK | 2:2 (2:0) | ||
| 11:00 | Sakaryaspor | - | Vanspor FK | 1:1 (1:1) | ||
| 11:00 | Serik Belediyespor | - | Çorum FK | 0:1 (0:1) | ||
| 11:00 | Sivas Belediyespor | - | Bayburt İl Özel İdare | 2:0 (2:0) | ||
| 11:00 | Turgutluspor | - | Bodrumspor | 0:2 (0:1) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Sakaryaspor | 24 | 15 | 7 | 2 | 49:15 | 34 | 52 |
| 2 |
|
1461 Trabzon FK | 24 | 15 | 7 | 2 | 42:18 | 24 | 52 |
| 3 |
|
Sivas Belediyespor | 24 | 13 | 6 | 5 | 44:20 | 24 | 45 |
| 4 |
|
Bodrumspor | 24 | 13 | 4 | 7 | 36:20 | 16 | 43 |
| 5 |
|
Vanspor FK | 24 | 12 | 6 | 6 | 35:31 | 4 | 42 |
| 6 |
|
Afjet Afyonspor | 24 | 11 | 8 | 5 | 45:27 | 18 | 41 |
| 7 |
|
Bayburt İl Özel İdare | 24 | 12 | 5 | 7 | 33:24 | 9 | 41 |
| 8 |
|
Somaspor | 24 | 12 | 5 | 7 | 39:32 | 7 | 41 |
| 9 |
|
Çorum FK | 24 | 11 | 7 | 6 | 36:21 | 15 | 40 |
| 10 |
|
Ankaraspor | 24 | 9 | 8 | 7 | 37:27 | 10 | 35 |
| 11 |
|
Inegölspor | 24 | 9 | 4 | 11 | 29:35 | -6 | 31 |
| 12 |
|
Serik Belediyespor | 24 | 9 | 3 | 12 | 29:33 | -4 | 30 |
| 13 |
|
Etimesgut Belediyespor | 24 | 7 | 8 | 9 | 28:33 | -5 | 29 |
| 14 |
|
Diyarbekirspor | 24 | 8 | 4 | 12 | 26:28 | -2 | 28 |
| 15 |
|
Sarıyer SK | 24 | 7 | 4 | 13 | 27:36 | -9 | 25 |
| 16 |
|
Adıyamanspor | 24 | 8 | 1 | 15 | 32:45 | -13 | 25 |
| 17 |
|
Turgutluspor | 24 | 5 | 8 | 11 | 21:41 | -20 | 23 |
| 18 |
|
Ergene Velimeşe | 24 | 6 | 3 | 15 | 26:47 | -21 | 21 |
| 19 |
|
Kahramanmaraşspor | 24 | 3 | 5 | 16 | 17:57 | -40 | 14 |
| 20 |
|
Niğde Anadolu FK | 24 | 1 | 5 | 18 | 18:59 | -41 | 8 |
| Promotion | |
| Play-off | |
| Relégation |
