 |
 |
|
|
| 27.01.2022 | 19:00 | Cruz Azul | - | FC Juárez | 1:0 (1:0) | |
| 22:45 | Puebla FC | - | CF Pachuca | 1:2 (0:1) | ||
| 28.01.2022 | 02:00 | Club León | - | Club Tijuana | 1:1 (0:0) | |
| 03:00 | CF Monterrey | - | Mazatlán FC | 4:0 (1:0) | ||
| 04:00 | Santos Laguna | - | Deportivo Toluca | 1:0 (0:0) | ||
| 19:00 | Club Necaxa | - | Deportivo Guadalajara | 0:3 (0:3) | ||
| 29.01.2022 | 00:00 | Atlético San Luis | - | CF América | 1:4 (1:1) | |
| 00:00 | Gallos Blancos | - | Pumas UNAM | 0:0 (0:0) | ||
| 02:00 | UANL Tigres | - | Atlas Guadalajara | 5:1 (2:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CF Monterrey | 4 | 4 | 0 | 0 | 12:0 | 12 | 12 |
| 2 |
|
Deportivo Guadalajara | 4 | 3 | 1 | 0 | 10:2 | 8 | 10 |
| 3 |
|
UANL Tigres | 4 | 3 | 1 | 0 | 11:4 | 7 | 10 |
| 4 |
|
CF Pachuca | 4 | 3 | 0 | 1 | 8:5 | 3 | 9 |
| 5 |
|
CF América | 4 | 2 | 1 | 1 | 6:4 | 2 | 7 |
| 6 |
|
Cruz Azul | 4 | 2 | 1 | 1 | 4:3 | 1 | 7 |
| 7 |
|
Club Tijuana | 4 | 1 | 3 | 0 | 8:7 | 1 | 6 |
| 8 |
|
Atlético San Luis | 4 | 1 | 2 | 1 | 5:7 | -2 | 5 |
| 9 |
|
Atlas Guadalajara | 4 | 1 | 2 | 1 | 4:7 | -3 | 5 |
| 10 |
|
Deportivo Toluca | 4 | 1 | 1 | 2 | 6:7 | -1 | 4 |
| 11 |
|
Santos Laguna | 4 | 1 | 1 | 2 | 3:4 | -1 | 4 |
| 12 |
|
Pumas UNAM | 4 | 1 | 1 | 2 | 1:2 | -1 | 4 |
| 13 |
|
Club Necaxa | 4 | 1 | 1 | 2 | 3:7 | -4 | 4 |
| 14 |
|
Gallos Blancos | 4 | 1 | 1 | 2 | 1:5 | -4 | 4 |
| 15 |
|
FC Juárez | 4 | 1 | 0 | 3 | 4:5 | -1 | 3 |
| 16 |
|
Mazatlán FC | 4 | 0 | 2 | 2 | 2:7 | -5 | 2 |
| 17 |
|
Club León | 4 | 0 | 1 | 3 | 2:8 | -6 | 1 |
|
Puebla FC | 4 | 0 | 1 | 3 | 2:8 | -6 | 1 | |
| Play-off |
