 |
 |
|
|
| 22.01.2022 | 19:00 | Atlas Guadalajara | - | Santos Laguna | 1:0 (1:0) | |
| 19:00 | Cruz Azul | - | Gallos Blancos | 0:1 (0:1) | ||
| 24.01.2022 | 02:00 | Mazatlán FC | - | Puebla FC | 0:0 (0:0) | |
| 25.01.2022 | 00:00 | Club Necaxa | - | Pumas UNAM | 1:0 (1:0) | |
| 02:00 | CF Pachuca | - | Club León | 3:0 (1:0) | ||
| 02:00 | CF América | - | CF Monterrey | 0:2 (0:1) | ||
| 04:00 | Deportivo Guadalajara | - | Deportivo Toluca | 2:0 (2:0) | ||
| 04:00 | Club Tijuana | - | Atlético San Luis | 2:2 (0:0) | ||
| 24.02.2022 | 04:00 | FC Juárez | - | UANL Tigres | 1:2 (0:1) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CF Monterrey | 3 | 3 | 0 | 0 | 8:0 | 8 | 9 |
| 2 |
|
Deportivo Guadalajara | 3 | 2 | 1 | 0 | 7:2 | 5 | 7 |
| 3 |
|
UANL Tigres | 3 | 2 | 1 | 0 | 6:3 | 3 | 7 |
| 4 |
|
CF Pachuca | 3 | 2 | 0 | 1 | 6:4 | 2 | 6 |
| 5 |
|
Club Tijuana | 3 | 1 | 2 | 0 | 7:6 | 1 | 5 |
| 6 |
|
Atlético San Luis | 3 | 1 | 2 | 0 | 4:3 | 1 | 5 |
| 7 |
|
Atlas Guadalajara | 3 | 1 | 2 | 0 | 3:2 | 1 | 5 |
| 8 |
|
Deportivo Toluca | 3 | 1 | 1 | 1 | 6:6 | 0 | 4 |
| 9 |
|
Cruz Azul | 3 | 1 | 1 | 1 | 3:3 | 0 | 4 |
| 10 |
|
Club Necaxa | 3 | 1 | 1 | 1 | 3:4 | -1 | 4 |
| 11 |
|
CF América | 3 | 1 | 1 | 1 | 2:3 | -1 | 4 |
| 12 |
|
FC Juárez | 3 | 1 | 0 | 2 | 4:4 | 0 | 3 |
| 13 |
|
Pumas UNAM | 3 | 1 | 0 | 2 | 1:2 | -1 | 3 |
| 14 |
|
Gallos Blancos | 3 | 1 | 0 | 2 | 1:5 | -4 | 3 |
| 15 |
|
Mazatlán FC | 3 | 0 | 2 | 1 | 2:3 | -1 | 2 |
| 16 |
|
Santos Laguna | 3 | 0 | 1 | 2 | 2:4 | -2 | 1 |
| 17 |
|
Puebla FC | 3 | 0 | 1 | 2 | 1:6 | -5 | 1 |
| 18 |
|
Club León | 3 | 0 | 0 | 3 | 1:7 | -6 | 0 |
| Play-off |
