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| 21.05.2011 | 17:30 | 1. FK Příbram | - | Zbrojovka Brno | 1:0 (0:0) | |
| 17:30 | 1. FC Slovácko | - | FK Mladá Boleslav | 1:2 (1:0) | ||
| 17:30 | FK Baumit Jablonec | - | Slavia Praha | 2:2 (2:1) | ||
| 17:30 | FK Ústí nad Labem | - | AC Sparta Praha | 1:3 (1:1) | ||
| 17:30 | Viktoria Plzeň | - | Baník Ostrava | 3:1 (2:1) | ||
| 17:30 | Dynamo České Budějovice | - | Sigma Olomouc | 1:0 (0:0) | ||
| 17:30 | Bohemians 1905 | - | FK Teplice | 1:1 (1:0) | ||
| 17:30 | FC Hradec Králové | - | Slovan Liberec | 1:0 (1:0) |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Viktoria Plzeň | 29 | 21 | 6 | 2 | 69:26 | 43 | 69 |
| 2 |
|
AC Sparta Praha | 29 | 21 | 2 | 6 | 51:20 | 31 | 65 |
| 3 |
|
FK Baumit Jablonec | 29 | 16 | 7 | 6 | 61:31 | 30 | 55 |
| 4 |
|
Sigma Olomouc | 29 | 13 | 5 | 11 | 45:28 | 17 | 44 |
| 5 |
|
FK Mladá Boleslav | 29 | 12 | 7 | 10 | 47:40 | 7 | 43 |
| 6 |
|
Bohemians 1905 | 29 | 12 | 7 | 10 | 33:30 | 3 | 43 |
| 7 |
|
Slovan Liberec | 29 | 12 | 6 | 11 | 42:33 | 9 | 42 |
| 8 |
|
FC Hradec Králové | 29 | 11 | 8 | 10 | 25:33 | -8 | 41 |
| 9 |
|
FK Teplice | 29 | 10 | 8 | 11 | 38:45 | -7 | 38 |
| 10 |
|
Slavia Praha | 29 | 8 | 13 | 8 | 38:36 | 2 | 37 |
| 11 |
|
Dynamo České Budějovice | 29 | 7 | 11 | 11 | 27:45 | -18 | 32 |
| 12 |
|
Baník Ostrava | 29 | 7 | 9 | 13 | 31:44 | -13 | 30 |
| 13 |
|
1. FC Slovácko | 29 | 8 | 6 | 15 | 26:42 | -16 | 30 |
| 14 |
|
1. FK Příbram | 29 | 7 | 7 | 15 | 20:36 | -16 | 28 |
| 15 |
|
Zbrojovka Brno | 29 | 7 | 3 | 19 | 30:51 | -21 | 24 |
| 16 |
|
FK Ústí nad Labem | 29 | 4 | 7 | 18 | 22:65 | -43 | 19 |
| Champions League Quali. | |
| Europa League | |
| Relégation |
