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| H (Match allé) | Atlético Goianiense | - | Corinthians SP | 2:0 (1:0) | ||
| R (match retour) | Corinthians SP | - | Atlético Goianiense | 4:1 (1:0) | ||
| H (Match allé): 28.07.2022 02:30 | R (match retour): 18.08.2022 02:30 | vainqueur: Corinthians SP | ||||
| H (Match allé) | Flamengo RJ | - | Athletico Paranaense | 0:0 (0:0) | ||
| R (match retour) | Athletico Paranaense | - | Flamengo RJ | 0:1 (0:0) | ||
| H (Match allé): 28.07.2022 02:30 | R (match retour): 18.08.2022 02:30 | vainqueur: Flamengo RJ | ||||
| H (Match allé) | São Paulo FC | - | América - MG | 1:0 (1:0) | ||
| R (match retour) | América - MG | - | São Paulo FC | 2:2 (1:2) | ||
| H (Match allé): 29.07.2022 01:00 | R (match retour): 19.08.2022 02:00 | vainqueur: São Paulo FC | ||||
| H (Match allé) | Fortaleza | - | Fluminense RJ | 0:1 (0:1) | ||
| R (match retour) | Fluminense RJ | - | Fortaleza | 2:2 (0:2) | ||
| H (Match allé): 29.07.2022 01:30 | R (match retour): 18.08.2022 01:00 | vainqueur: Fluminense RJ | ||||
