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| 19.02.2022 | 13:45 | Egnatia Rrogozhine | - | KF Skënderbeu | 2:0 (1:0) | |
| 16:45 | FK Partizani | - | FK Vllaznia | 1:1 (0:1) | ||
| 20.02.2022 | 13:45 | KS Kastrioti | - | KF Tiranë | 2:1 (1:0) | |
| 13:45 | KF Laçi | - | FK Kukësi | 3:0 (2:0) | ||
| 16:45 | KF Teuta Durrës | - | Dinamo Tiranë | 1:0 (1:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
KF Tiranë | 21 | 14 | 4 | 3 | 39:15 | 24 | 46 |
| 2 |
|
KF Laçi | 21 | 13 | 4 | 4 | 34:16 | 18 | 43 |
| 3 |
|
FK Kukësi | 21 | 11 | 4 | 6 | 36:24 | 12 | 37 |
| 4 |
|
FK Vllaznia | 21 | 8 | 10 | 3 | 30:21 | 9 | 34 |
| 5 |
|
FK Partizani | 21 | 7 | 8 | 6 | 25:18 | 7 | 29 |
| 6 |
|
KF Teuta Durrës | 21 | 6 | 6 | 9 | 22:32 | -10 | 24 |
| 7 |
|
Egnatia Rrogozhine | 21 | 4 | 7 | 10 | 15:29 | -14 | 19 |
| 8 |
|
Dinamo Tiranë | 21 | 4 | 7 | 10 | 12:27 | -15 | 19 |
| 9 |
|
KS Kastrioti | 21 | 5 | 3 | 13 | 16:35 | -19 | 18 |
| 10 |
|
KF Skënderbeu | 21 | 3 | 7 | 11 | 16:28 | -12 | 16 |
| Champions League Quali. | |
| Relégation | |
| Relégation |
