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| 13.02.2022 | 13:45 | FK Kukësi | - | KS Kastrioti | 4:0 (2:0) | |
| 16:45 | FK Vllaznia | - | KF Teuta Durrës | 4:2 (3:2) | ||
| 14.02.2022 | 16:45 | Dinamo Tiranë | - | KF Laçi | 0:1 (0:1) | |
| 16:45 | KF Skënderbeu | - | FK Partizani | 1:2 (1:0) | ||
| 19:45 | KF Tiranë | - | Egnatia Rrogozhine | 2:0 (1:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
KF Tiranë | 20 | 14 | 4 | 2 | 38:13 | 25 | 46 |
| 2 |
|
KF Laçi | 20 | 12 | 4 | 4 | 31:16 | 15 | 40 |
| 3 |
|
FK Kukësi | 20 | 11 | 4 | 5 | 36:21 | 15 | 37 |
| 4 |
|
FK Vllaznia | 20 | 8 | 9 | 3 | 29:20 | 9 | 33 |
| 5 |
|
FK Partizani | 20 | 7 | 7 | 6 | 24:17 | 7 | 28 |
| 6 |
|
KF Teuta Durrës | 20 | 5 | 6 | 9 | 21:32 | -11 | 21 |
| 7 |
|
Dinamo Tiranë | 20 | 4 | 7 | 9 | 12:26 | -14 | 19 |
| 8 |
|
KF Skënderbeu | 20 | 3 | 7 | 10 | 16:26 | -10 | 16 |
| 9 |
|
Egnatia Rrogozhine | 20 | 3 | 7 | 10 | 13:29 | -16 | 16 |
| 10 |
|
KS Kastrioti | 20 | 4 | 3 | 13 | 14:34 | -20 | 15 |
| Champions League Quali. | |
| Relégation | |
| Relégation |
