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| ANAPROF | 19.02.2021 | Herrera FC | - | Independiente de La Chorrera | 0:1 | ??? |
| ANAPROF | 05.03.2021 | Herrera FC | - | Veraguas Club Deportivo | 1:2 | ??? |
| ANAPROF | 15.03.2021 | Herrera FC | - | San Francisco FC | 1:0 | ??? |
| ANAPROF | 22.03.2021 | Herrera FC | - | Árabe Unido | 0:0 | ??? |
| ANAPROF | 28.03.2021 | Herrera FC | - | Tauro FC | 1:1 | ??? |
| ANAPROF | 05.04.2021 | Herrera FC | - | Sporting San Miguelito | 2:0 | ??? |
| ANAPROF | 25.04.2021 | Herrera FC | - | Atlético Chiriquí | 3:0 | ??? |
| ANAPROF | 09.05.2021 | Herrera FC | - | UD Universitario | 2:0 | ??? |
| ANAPROF | 15.08.2021 | Herrera FC | - | Atlético Chiriquí | 0:0 | ??? |
| ANAPROF | 04.09.2021 | Herrera FC | - | UD Universitario | 1:2 | ??? |
| ANAPROF | 18.09.2021 | Herrera FC | - | Deportivo del Este | 1:1 | ??? |
| ANAPROF | 10.10.2021 | Herrera FC | - | Plaza Amador | 0:2 | ??? |
| ANAPROF | 18.10.2021 | Herrera FC | - | Alianza | 1:1 | ??? |
| ANAPROF | 24.10.2021 | Herrera FC | - | Independiente de La Chorrera | 2:1 | ??? |
| ANAPROF | 07.11.2021 | Herrera FC | - | Veraguas Club Deportivo | 1:1 | ??? |
| ANAPROF | 13.11.2021 | Herrera FC | - | San Francisco FC | 2:1 | ??? |
| ANAPROF | 06.12.2021 | Herrera FC | - | Veraguas Club Deportivo | 1:0 | ??? |
Panama