| 4. Journée | 22.05.2022 | FC Cincinnati | - | New England Revolution | 2:3 | ||||
| 4. Journée | 29.05.2022 | New England Revolution | - | Philadelphia Union | 1:1 | ||||
| 5. Journée | 12.06.2022 | Sporting Kansas City | - | New England Revolution | 1:2 | ||||
| 5. Journée | 16.06.2022 | New England Revolution | - | Orlando City | 1:1 |  |
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| 5. Journée | 19.06.2022 | New England Revolution | - | Minnesota United FC | 2:1 |  |
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| 5. Journée | 27.06.2022 | Vancouver Whitecaps | - | New England Revolution | 0:0 | ||||
| 6. Journée | 04.07.2022 | New England Revolution | - | FC Cincinnati | 2:2 | |
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| 6. Journée | 09.07.2022 | New York City FC | - | New England Revolution | 4:2 | ||||
| 6. Journée | 17.07.2022 | Philadelphia Union | - | New England Revolution | 2:1 | ||||
| 8. Journée | 18.09.2022 | New England Revolution | - | CF Montréal | 0:1 | ||||
| 9. Journée | 01.10.2022 | New England Revolution | - | Atlanta United FC | 2:1 | ||||
| 9. Journée | 09.10.2022 | Chicago Fire | - | New England Revolution | 1:1 | |
Colombie