| 1. Journée | 02.08.2021 | Kilmarnock FC | - | Ayr United | 2:0 |  |
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| 2. Journée | 07.08.2021 | Ayr United | - | Arbroath FC | 2:2 | ||||
| 3. Journée | 21.08.2021 | Inverness CT | - | Ayr United | 1:0 | ||||
| 4. Journée | 07.09.2021 | Ayr United | - | Raith Rovers | 0:2 | ||||
| 5. Journée | 11.09.2021 | Ayr United | - | Dunfermline Athletic | 3:1 |  |
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| 6. Journée | 18.09.2021 | Hamilton Academical | - | Ayr United | 0:2 | ||||
| 7. Journée | 25.09.2021 | Ayr United | - | Greenock Morton FC | 0:0 | ||||
| 8. Journée | 02.10.2021 | Partick Thistle | - | Ayr United | 4:0 | ||||
| 9. Journée | 16.10.2021 | Ayr United | - | Queen Of The South | 2:1 | ||||
| 10. Journée | 23.10.2021 | Arbroath FC | - | Ayr United | 1:1 | ||||
| 11. Journée | 26.10.2021 | Ayr United | - | Kilmarnock FC | 0:1 | ||||
| 12. Journée | 30.10.2021 | Raith Rovers | - | Ayr United | 2:1 | ||||
| 15. Journée | 20.11.2021 | Dunfermline Athletic | - | Ayr United | 3:0 | ||||
| 17. Journée | 10.12.2021 | Ayr United | - | Hamilton Academical | 1:1 | ||||
| 18. Journée | 18.12.2021 | Queen Of The South | - | Ayr United | 3:0 |
Angleterre