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| 18.12.2021 | 11:00 | Karacabey Belediyespor | - | Nazilli Belediyespor | 0:2 (0:1) | |
| 19.12.2021 | Kastamonuspor | - | Isparta 32 SK | pas disputer | ||
| 11:00 | Bucaspor 1928 | - | 24 Erzincanspor | 2:0 (0:0) | ||
| 11:00 | Amed SK | - | Akhisar Belediyespor | 0:0 (0:0) | ||
| 11:00 | Eskişehirspor | - | Ankara Demirspor | 2:2 (1:0) | ||
| 11:00 | Kırklarelispor | - | Uşakspor | 0:0 (0:0) | ||
| 11:00 | Pazarspor | - | Pendikspor | 0:1 (0:0) | ||
| 11:00 | Şanlıurfaspor | - | Kırşehir Belediyespor | 1:1 (0:0) | ||
| 11:00 | Zonguldak Kömürspor | - | Tarsus Idman Yurdu | 0:0 (0:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Pendikspor | 16 | 12 | 3 | 1 | 24:9 | 15 | 39 |
| 2 |
|
Bucaspor 1928 | 16 | 8 | 2 | 6 | 24:19 | 5 | 26 |
| 3 |
|
Isparta 32 SK | 16 | 7 | 4 | 5 | 15:11 | 4 | 25 |
| 4 |
|
Amed SK | 16 | 7 | 4 | 5 | 20:19 | 1 | 25 |
| 5 |
|
Nazilli Belediyespor | 16 | 6 | 6 | 4 | 15:13 | 2 | 24 |
| 6 |
|
Kırklarelispor | 16 | 5 | 8 | 3 | 24:16 | 8 | 23 |
| 7 |
|
Şanlıurfaspor | 16 | 5 | 8 | 3 | 19:17 | 2 | 23 |
| 8 |
|
Pazarspor | 16 | 7 | 1 | 8 | 23:24 | -1 | 22 |
| 9 |
|
Kırşehir Belediyespor | 16 | 5 | 6 | 5 | 17:15 | 2 | 21 |
| 10 |
|
Ankara Demirspor | 16 | 5 | 6 | 5 | 15:15 | 0 | 21 |
| 11 |
|
Akhisar Belediyespor | 17 | 6 | 3 | 8 | 20:24 | -4 | 21 |
| 12 |
|
Uşakspor | 16 | 5 | 6 | 5 | 13:17 | -4 | 21 |
| 13 |
|
24 Erzincanspor | 16 | 5 | 5 | 6 | 22:19 | 3 | 20 |
| 14 |
|
Tarsus Idman Yurdu | 16 | 5 | 4 | 7 | 13:15 | -2 | 19 |
| 15 |
|
1922 Konyaspor | 16 | 4 | 6 | 6 | 23:21 | 2 | 18 |
| 16 |
|
Zonguldak Kömürspor | 16 | 5 | 3 | 8 | 18:25 | -7 | 18 |
| 17 |
|
Karacabey Belediyespor | 16 | 5 | 1 | 10 | 21:28 | -7 | 16 |
| 18 |
|
Eskişehirspor | 17 | 3 | 4 | 10 | 16:35 | -19 | 10 |
| 19 |
|
Kastamonuspor | 0 | 0 | 0 | 0 | 0:0 | 0 | 0 |
| Promotion | |
| Play-off | |
| Relégation |
