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| 20.11.2021 | 11:00 | Karacabey Belediyespor | - | Akhisar Belediyespor | 3:0 (2:0) | |
| 11:00 | Nazilli Belediyespor | - | Kırşehir Belediyespor | 2:1 (0:0) | ||
| 21.11.2021 | Kastamonuspor | - | Bucaspor 1928 | pas disputer | ||
| 11:00 | Amed SK | - | 1922 Konyaspor | 4:3 (2:0) | ||
| 11:00 | Ankara Demirspor | - | Uşakspor | 0:0 (0:0) | ||
| 11:00 | Eskişehirspor | - | Pendikspor | 0:1 (0:0) | ||
| 11:00 | Kırklarelispor | - | Tarsus Idman Yurdu | 2:0 (1:0) | ||
| 11:00 | Pazarspor | - | 24 Erzincanspor | 2:4 (2:2) | ||
| 11:00 | Şanlıurfaspor | - | Isparta 32 SK | 0:2 (0:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Pendikspor | 12 | 9 | 2 | 1 | 18:7 | 11 | 29 |
| 2 |
|
Isparta 32 SK | 13 | 6 | 3 | 4 | 13:8 | 5 | 21 |
| 3 |
|
Amed SK | 12 | 6 | 3 | 3 | 17:13 | 4 | 21 |
| 4 |
|
Şanlıurfaspor | 12 | 5 | 4 | 3 | 16:14 | 2 | 19 |
| 5 |
|
Bucaspor 1928 | 13 | 6 | 1 | 6 | 19:18 | 1 | 19 |
| 6 |
|
Nazilli Belediyespor | 13 | 5 | 4 | 4 | 13:13 | 0 | 19 |
| 7 |
|
Kırklarelispor | 12 | 4 | 6 | 2 | 18:13 | 5 | 18 |
| 8 |
|
Tarsus Idman Yurdu | 13 | 5 | 3 | 5 | 13:13 | 0 | 18 |
| 9 |
|
Ankara Demirspor | 13 | 5 | 3 | 5 | 12:12 | 0 | 18 |
| 10 |
|
1922 Konyaspor | 14 | 4 | 5 | 5 | 21:18 | 3 | 17 |
| 11 |
|
Pazarspor | 12 | 5 | 1 | 6 | 19:20 | -1 | 16 |
| 12 |
|
Akhisar Belediyespor | 13 | 5 | 1 | 7 | 14:16 | -2 | 16 |
| 13 |
|
Uşakspor | 12 | 4 | 4 | 4 | 11:15 | -4 | 16 |
| 14 |
|
Kırşehir Belediyespor | 12 | 4 | 3 | 5 | 12:12 | 0 | 15 |
| 15 |
|
24 Erzincanspor | 13 | 3 | 5 | 5 | 13:14 | -1 | 14 |
| 16 |
|
Zonguldak Kömürspor | 12 | 4 | 2 | 6 | 15:18 | -3 | 14 |
| 17 |
|
Karacabey Belediyespor | 12 | 4 | 1 | 7 | 18:20 | -2 | 13 |
| 18 |
|
Eskişehirspor | 13 | 3 | 1 | 9 | 12:30 | -18 | 7 |
| 19 |
|
Kastamonuspor | 0 | 0 | 0 | 0 | 0:0 | 0 | 0 |
| Promotion | |
| Play-off | |
| Relégation |
