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| 13.11.2010 | 13:00 | FK Inđija | - | FK Metalac | 1:0 (0:0) | |
| 13:00 | FK Sloboda Point Sevojno | - | FK Čukarički | 4:0 (2:0) | ||
| 13:00 | OFK Beograd | - | FK Jagodina | 0:1 (0:1) | ||
| 13:00 | Borac Čačak | - | FK Smederevo | 0:1 (0:0) | ||
| 18:00 | Partizan | - | FK Javor | 4:1 (1:0) | ||
| 14.11.2010 | 13:00 | Hajduk Rodić | - | BSK Borča | 0:1 (0:0) | |
| 13:00 | FK Rad Beograd | - | Crvena Zvezda | 0:1 (0:0) | ||
| 13:00 | Spartak Zlatibor Voda | - | Vojvodina | 0:1 (0:1) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Partizan | 12 | 10 | 1 | 1 | 27:7 | 20 | 31 |
| 2 |
|
Crvena Zvezda | 12 | 9 | 1 | 2 | 15:5 | 10 | 28 |
| 3 |
|
Vojvodina | 12 | 7 | 4 | 1 | 15:2 | 13 | 25 |
| 4 |
|
FK Rad Beograd | 12 | 7 | 3 | 2 | 14:6 | 8 | 24 |
| 5 |
|
FK Sloboda Point Sevojno | 12 | 5 | 5 | 2 | 12:8 | 4 | 20 |
| 6 |
|
FK Jagodina | 12 | 5 | 3 | 4 | 11:10 | 1 | 18 |
| 7 |
|
Spartak Zlatibor Voda | 12 | 4 | 5 | 3 | 13:10 | 3 | 17 |
| 8 |
|
FK Smederevo | 12 | 3 | 7 | 2 | 13:10 | 3 | 16 |
| 9 |
|
OFK Beograd | 12 | 4 | 3 | 5 | 10:11 | -1 | 15 |
| 10 |
|
FK Javor | 12 | 3 | 5 | 4 | 9:11 | -2 | 14 |
| 11 |
|
FK Inđija | 12 | 3 | 4 | 5 | 11:14 | -3 | 13 |
| 12 |
|
BSK Borča | 12 | 3 | 4 | 5 | 7:14 | -7 | 13 |
| 13 |
|
Borac Čačak | 12 | 2 | 6 | 4 | 6:13 | -7 | 12 |
| 14 |
|
Hajduk Rodić | 12 | 1 | 2 | 9 | 7:18 | -11 | 5 |
| 15 |
|
FK Metalac | 12 | 1 | 2 | 9 | 5:17 | -12 | 5 |
| 16 |
|
FK Čukarički | 12 | 0 | 3 | 9 | 2:21 | -19 | 3 |
| Champions League Quali. | |
| Europa League | |
| Relégation |
