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| 19.04.2013 | 15:00 | FK Amkar Perm | - | Rubin Kazan | 1:1 (0:1) | |
| 20.04.2013 | 11:30 | Mordovia Saransk | - | Volga Nizhniy Novgorod | 1:3 (1:0) | |
| 14:00 | Krylia Sovetov | - | Spartak Vladikavkaz | 2:1 (2:0) | ||
| 16:30 | Kuban Krasnodar (1928-2018) | - | Lokomotiv Moskva | 0:0 (0:0) | ||
| 21.04.2013 | 11:30 | CSKA Moskva | - | Spartak Moskva | 2:2 (0:1) | |
| 14:00 | Zenit St. Petersburg | - | FK Krasnodar | 1:0 (0:0) | ||
| 16:30 | Anzhi Makhachkala | - | Dinamo Moskva | 3:3 (1:1) | ||
| 22.04.2013 | 17:00 | FK Rostov | - | Terek Grozny | 0:3 (0:2) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CSKA Moskva | 25 | 18 | 3 | 4 | 44:19 | 25 | 57 |
| 2 |
|
Zenit St. Petersburg | 25 | 16 | 5 | 4 | 43:21 | 22 | 53 |
| 3 |
|
Anzhi Makhachkala | 25 | 13 | 8 | 4 | 41:28 | 13 | 47 |
| 4 |
|
Spartak Moskva | 25 | 12 | 5 | 8 | 44:36 | 8 | 41 |
| 5 |
|
Rubin Kazan | 25 | 12 | 5 | 8 | 31:21 | 10 | 41 |
| 6 |
|
Kuban Krasnodar (1928-2018) | 25 | 11 | 7 | 7 | 39:26 | 13 | 40 |
| 7 |
|
Dinamo Moskva | 25 | 12 | 4 | 9 | 35:30 | 5 | 40 |
| 8 |
|
Terek Grozny | 25 | 11 | 5 | 9 | 30:36 | -6 | 38 |
| 9 |
|
FK Krasnodar | 25 | 10 | 5 | 10 | 39:33 | 6 | 35 |
| 10 |
|
Lokomotiv Moskva | 25 | 9 | 7 | 9 | 28:26 | 2 | 34 |
| 11 |
|
FK Amkar Perm | 25 | 6 | 7 | 12 | 28:39 | -11 | 25 |
| 12 |
|
FK Rostov | 25 | 6 | 7 | 12 | 23:32 | -9 | 25 |
| 13 |
|
Volga Nizhniy Novgorod | 25 | 6 | 6 | 13 | 25:40 | -15 | 24 |
| 14 |
|
Krylia Sovetov | 25 | 6 | 5 | 14 | 24:43 | -19 | 23 |
| 15 |
|
Mordovia Saransk | 25 | 4 | 4 | 17 | 24:48 | -24 | 16 |
| 16 |
|
Spartak Vladikavkaz | 25 | 3 | 7 | 15 | 23:43 | -20 | 16 |
| Champions League | |
| Champions League Quali. | |
| Europa League | |
| Europa League Quali. | |
| Relégation | |
| Relégation |
