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| 15.03.2013 | 16:00 | FK Rostov | - | Volga Nizhniy Novgorod | 1:2 (0:1) | |
| 16.03.2013 | 10:30 | Spartak Moskva | - | Lokomotiv Moskva | 0:0 (0:0) | |
| 13:00 | FK Amkar Perm | - | Spartak Vladikavkaz | 5:1 (3:0) | ||
| 15:30 | Kuban Krasnodar (1928-2018) | - | Dinamo Moskva | 1:1 (1:1) | ||
| 17.03.2013 | 10:30 | CSKA Moskva | - | FK Krasnodar | 1:0 (1:0) | |
| 12:45 | Anzhi Makhachkala | - | Krylia Sovetov | 1:1 (0:0) | ||
| 15:00 | Terek Grozny | - | Rubin Kazan | 0:0 (0:0) | ||
| 17:15 | Zenit St. Petersburg | - | Mordovia Saransk | 1:0 (0:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CSKA Moskva | 21 | 16 | 1 | 4 | 36:17 | 19 | 49 |
| 2 |
|
Anzhi Makhachkala | 21 | 12 | 6 | 3 | 35:21 | 14 | 42 |
| 3 |
|
Zenit St. Petersburg | 21 | 12 | 5 | 4 | 37:21 | 16 | 41 |
| 4 |
|
Spartak Moskva | 21 | 11 | 3 | 7 | 38:31 | 7 | 36 |
| 5 |
|
Kuban Krasnodar (1928-2018) | 21 | 11 | 3 | 7 | 35:22 | 13 | 36 |
| 6 |
|
Rubin Kazan | 21 | 11 | 2 | 8 | 27:19 | 8 | 35 |
| 7 |
|
Dinamo Moskva | 21 | 11 | 1 | 9 | 30:26 | 4 | 34 |
| 8 |
|
Terek Grozny | 21 | 10 | 3 | 8 | 24:30 | -6 | 33 |
| 9 |
|
Lokomotiv Moskva | 21 | 9 | 5 | 7 | 27:22 | 5 | 32 |
| 10 |
|
FK Krasnodar | 21 | 9 | 4 | 8 | 35:29 | 6 | 31 |
| 11 |
|
FK Amkar Perm | 21 | 6 | 4 | 11 | 25:34 | -9 | 22 |
| 12 |
|
FK Rostov | 21 | 5 | 6 | 10 | 21:27 | -6 | 21 |
| 13 |
|
Volga Nizhniy Novgorod | 21 | 5 | 5 | 11 | 21:33 | -12 | 20 |
| 14 |
|
Krylia Sovetov | 21 | 4 | 5 | 12 | 19:39 | -20 | 17 |
| 15 |
|
Mordovia Saransk | 21 | 3 | 3 | 15 | 20:42 | -22 | 12 |
| 16 |
|
Spartak Vladikavkaz | 21 | 2 | 6 | 13 | 19:36 | -17 | 12 |
| Champions League | |
| Champions League Quali. | |
| Europa League | |
| Europa League Quali. | |
| Relégation | |
| Relégation |
