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| 01.04.2022 | 18:00 | FKS Stal Mielec | - | KS Cracovia | 1:2 (0:2) | |
| 20:30 | Śląsk Wrocław | - | Lech Poznań | 0:1 (0:0) | ||
| 02.04.2022 | 15:00 | Warta Poznań | - | Raków Częstochowa | 0:2 (0:1) | |
| 17:30 | Górnik Łęczna | - | Pogoń Szczecin | 0:4 (0:2) | ||
| 20:00 | Legia Warszawa | - | Lechia Gdańsk | 2:1 (1:0) | ||
| 03.04.2022 | 12:30 | Bruk-Bet Termalica Nieciecza | - | Radomiak Radom | 1:1 (0:1) | |
| 15:00 | Jagiellonia Białystok | - | Zagłębie Lubin | 2:1 (0:0) | ||
| 17:30 | Wisła Kraków | - | Piast Gliwice | 2:2 (1:0) | ||
| 04.04.2022 | 18:00 | Wisła Płock | - | Górnik Zabrze | 3:2 (2:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Pogoń Szczecin | 27 | 16 | 8 | 3 | 53:22 | 31 | 56 |
| 2 |
|
Lech Poznań | 27 | 16 | 7 | 4 | 53:19 | 34 | 55 |
| 3 |
|
Raków Częstochowa | 27 | 16 | 7 | 4 | 48:25 | 23 | 55 |
| 4 |
|
Lechia Gdańsk | 27 | 12 | 7 | 8 | 40:31 | 9 | 43 |
| 5 |
|
Radomiak Radom | 27 | 10 | 12 | 5 | 34:27 | 7 | 42 |
| 6 |
|
Wisła Płock | 27 | 12 | 3 | 12 | 39:39 | 0 | 39 |
| 7 |
|
Piast Gliwice | 27 | 10 | 8 | 9 | 35:31 | 4 | 38 |
| 8 |
|
Górnik Zabrze | 27 | 10 | 7 | 10 | 38:36 | 2 | 37 |
| 9 |
|
KS Cracovia | 27 | 9 | 8 | 10 | 34:37 | -3 | 35 |
| 10 |
|
Legia Warszawa | 27 | 11 | 2 | 14 | 33:36 | -3 | 35 |
| 11 |
|
FKS Stal Mielec | 27 | 8 | 9 | 10 | 32:37 | -5 | 33 |
| 12 |
|
Jagiellonia Białystok | 27 | 8 | 9 | 10 | 31:41 | -10 | 33 |
| 13 |
|
Śląsk Wrocław | 27 | 7 | 9 | 11 | 34:39 | -5 | 30 |
| 14 |
|
Warta Poznań | 27 | 7 | 9 | 11 | 26:31 | -5 | 30 |
| 15 |
|
Zagłębie Lubin | 27 | 8 | 4 | 15 | 28:48 | -20 | 28 |
| 16 |
|
Wisła Kraków | 27 | 6 | 7 | 14 | 27:43 | -16 | 25 |
| 17 |
|
Bruk-Bet Termalica Nieciecza | 27 | 5 | 9 | 13 | 28:47 | -19 | 24 |
| 18 |
|
Górnik Łęczna | 27 | 5 | 9 | 13 | 24:48 | -24 | 24 |
| Champions League Quali. | |
| Relégation |
