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| 14.05.2022 | 12:00 | Sparta Rotterdam (J) | - | Excelsior Maassluis | 3:0 (0:0) | |
| 14:30 | GVVV | - | ASWH Ido-Ambacht | 6:0 (3:0) | ||
| 14:30 | HHC Hardenberg | - | Quick Boys | 3:1 (1:0) | ||
| 14:30 | VV Noordwijk | - | Amsterdamsche FC | 1:1 (0:0) | ||
| 14:30 | SVV Scheveningen | - | Rijnsburgse Boys | 0:2 (0:0) | ||
| 15:00 | Kozakken Boys | - | Koninklijke HFC | 3:0 (2:0) | ||
| 15:00 | SV Spakenburg | - | IJsselmeervogels | 1:1 (1:0) | ||
| 15:30 | Jong FC Volendam | - | De Treffers | 3:0 (2:0) | ||
| 15:30 | VV Katwijk | - | TEC VV | 6:0 (2:0) |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
VV Katwijk | 30 | 20 | 5 | 5 | 67:29 | 38 | 65 |
| 2 |
|
HHC Hardenberg | 30 | 17 | 4 | 9 | 50:38 | 12 | 55 |
| 3 |
|
Koninklijke HFC | 30 | 15 | 8 | 7 | 46:31 | 15 | 53 |
| 4 |
|
Sparta Rotterdam (J) | 30 | 16 | 5 | 9 | 53:43 | 10 | 53 |
| 5 |
|
Rijnsburgse Boys | 30 | 16 | 3 | 11 | 59:38 | 21 | 51 |
| 6 |
|
Amsterdamsche FC | 30 | 13 | 7 | 10 | 52:43 | 9 | 46 |
| 7 |
|
VV Noordwijk | 30 | 13 | 6 | 11 | 42:40 | 2 | 45 |
| 8 |
|
SV Spakenburg | 30 | 12 | 6 | 12 | 58:54 | 4 | 42 |
| 9 |
|
SVV Scheveningen | 30 | 11 | 9 | 10 | 37:40 | -3 | 42 |
| 10 |
|
Quick Boys | 30 | 11 | 8 | 11 | 39:44 | -5 | 41 |
| 11 |
|
Excelsior Maassluis | 30 | 12 | 5 | 13 | 43:50 | -7 | 41 |
| 12 |
|
IJsselmeervogels | 30 | 12 | 3 | 15 | 40:42 | -2 | 39 |
| 13 |
|
De Treffers | 30 | 11 | 4 | 15 | 35:44 | -9 | 37 |
| 14 |
|
Jong FC Volendam | 30 | 11 | 3 | 16 | 59:61 | -2 | 36 |
| 15 |
|
TEC VV | 30 | 9 | 8 | 13 | 36:56 | -20 | 35 |
| 16 |
|
Kozakken Boys | 30 | 7 | 9 | 14 | 39:56 | -17 | 30 |
| 17 |
|
GVVV | 30 | 7 | 7 | 16 | 38:48 | -10 | 28 |
| 18 |
|
ASWH Ido-Ambacht | 30 | 5 | 4 | 21 | 30:66 | -36 | 19 |
| Relégation | |
| Relégation | |
| Relégation |
