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| 16.04.2022 | 12:15 | Jong FC Volendam | - | SVV Scheveningen | 0:2 (0:0) | |
| 14:30 | GVVV | - | VV Katwijk | 1:3 (0:0) | ||
| 14:30 | VV Noordwijk | - | HHC Hardenberg | 0:2 (0:1) | ||
| 14:30 | Amsterdamsche FC | - | Koninklijke HFC | 3:3 (0:1) | ||
| 15:00 | IJsselmeervogels | - | Excelsior Maassluis | 0:2 (0:1) | ||
| 15:00 | Kozakken Boys | - | Sparta Rotterdam (J) | 0:0 (0:0) | ||
| 15:00 | Quick Boys | - | SV Spakenburg | 1:0 (1:0) | ||
| 15:00 | De Treffers | - | Rijnsburgse Boys | 2:1 (1:0) | ||
| 15:30 | TEC VV | - | ASWH Ido-Ambacht | 3:0 (1:0) |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
VV Katwijk | 25 | 16 | 5 | 4 | 52:25 | 27 | 53 |
| 2 |
|
Koninklijke HFC | 25 | 13 | 7 | 5 | 40:26 | 14 | 46 |
| 3 |
|
HHC Hardenberg | 25 | 13 | 4 | 8 | 38:32 | 6 | 43 |
| 4 |
|
Amsterdamsche FC | 25 | 12 | 6 | 7 | 48:33 | 15 | 42 |
| 5 |
|
Quick Boys | 25 | 11 | 8 | 6 | 37:29 | 8 | 41 |
| 6 |
|
Sparta Rotterdam (J) | 25 | 12 | 5 | 8 | 42:40 | 2 | 41 |
| 7 |
|
Rijnsburgse Boys | 25 | 12 | 3 | 10 | 49:33 | 16 | 39 |
| 8 |
|
VV Noordwijk | 25 | 11 | 5 | 9 | 35:34 | 1 | 38 |
| 9 |
|
Excelsior Maassluis | 25 | 10 | 4 | 11 | 37:43 | -6 | 34 |
| 10 |
|
De Treffers | 25 | 10 | 3 | 12 | 29:31 | -2 | 33 |
| 11 |
|
SVV Scheveningen | 25 | 8 | 9 | 8 | 29:35 | -6 | 33 |
| 12 |
|
SV Spakenburg | 25 | 9 | 5 | 11 | 44:46 | -2 | 32 |
| 13 |
|
Jong FC Volendam | 25 | 9 | 3 | 13 | 45:47 | -2 | 30 |
| 14 |
|
TEC VV | 25 | 8 | 6 | 11 | 33:47 | -14 | 30 |
| 15 |
|
IJsselmeervogels | 25 | 9 | 2 | 14 | 30:39 | -9 | 29 |
| 16 |
|
Kozakken Boys | 25 | 6 | 8 | 11 | 30:42 | -12 | 26 |
| 17 |
|
GVVV | 25 | 4 | 7 | 14 | 25:42 | -17 | 19 |
| 18 |
|
ASWH Ido-Ambacht | 25 | 5 | 4 | 16 | 29:48 | -19 | 19 |
| Relégation | |
| Relégation | |
| Relégation |
