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| 12.03.2022 | 14:30 | VV Noordwijk | - | SVV Scheveningen | 1:0 (1:0) | |
| 14:30 | Amsterdamsche FC | - | Quick Boys | 2:2 (1:2) | ||
| 15:00 | ASWH Ido-Ambacht | - | Koninklijke HFC | 2:2 (2:1) | ||
| 15:00 | Excelsior Maassluis | - | Rijnsburgse Boys | 3:2 (0:2) | ||
| 15:30 | HHC Hardenberg | - | Kozakken Boys | 2:3 (0:1) | ||
| 15:30 | VV Katwijk | - | Jong FC Volendam | 3:2 (2:2) | ||
| 13.03.2022 | 14:30 | TEC VV | - | Sparta Rotterdam (J) | 1:1 (0:0) | |
| 29.03.2022 | 19:30 | GVVV | - | SV Spakenburg | 4:0 (4:0) | |
| 20:00 | IJsselmeervogels | - | De Treffers | 1:0 (1:0) |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
VV Katwijk | 18 | 14 | 2 | 2 | 42:16 | 26 | 44 |
| 2 |
|
Amsterdamsche FC | 18 | 9 | 5 | 4 | 35:20 | 15 | 32 |
| 3 |
|
Koninklijke HFC | 18 | 9 | 5 | 4 | 27:20 | 7 | 32 |
| 4 |
|
HHC Hardenberg | 18 | 9 | 4 | 5 | 26:19 | 7 | 31 |
| 5 |
|
De Treffers | 18 | 8 | 3 | 7 | 21:20 | 1 | 27 |
| 6 |
|
Sparta Rotterdam (J) | 18 | 8 | 3 | 7 | 32:33 | -1 | 27 |
| 7 |
|
VV Noordwijk | 18 | 8 | 3 | 7 | 23:25 | -2 | 27 |
| 8 |
|
Quick Boys | 18 | 6 | 6 | 6 | 25:24 | 1 | 24 |
| 9 |
|
Excelsior Maassluis | 18 | 7 | 3 | 8 | 26:28 | -2 | 24 |
| 10 |
|
SVV Scheveningen | 18 | 6 | 6 | 6 | 20:26 | -6 | 24 |
| 11 |
|
Rijnsburgse Boys | 18 | 7 | 2 | 9 | 31:27 | 4 | 23 |
| 12 |
|
SV Spakenburg | 18 | 6 | 4 | 8 | 35:36 | -1 | 22 |
| 13 |
|
Jong FC Volendam | 18 | 6 | 3 | 9 | 36:35 | 1 | 21 |
| 14 |
|
Kozakken Boys | 18 | 5 | 6 | 7 | 24:31 | -7 | 21 |
| 15 |
|
IJsselmeervogels | 18 | 6 | 2 | 10 | 22:29 | -7 | 20 |
| 16 |
|
TEC VV | 18 | 5 | 5 | 8 | 20:36 | -16 | 20 |
| 17 |
|
ASWH Ido-Ambacht | 18 | 5 | 4 | 9 | 25:29 | -4 | 19 |
| 18 |
|
GVVV | 18 | 3 | 4 | 11 | 15:31 | -16 | 13 |
| Relégation | |
| Relégation | |
| Relégation |
