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| 26.02.2022 | 14:30 | GVVV | - | Quick Boys | 1:1 (0:0) | |
| 14:30 | Amsterdamsche FC | - | VV Noordwijk | 4:1 (4:0) | ||
| 15:00 | ASWH Ido-Ambacht | - | Excelsior Maassluis | 2:1 (2:1) | ||
| 15:00 | Jong FC Volendam | - | Kozakken Boys | 3:0 (1:0) | ||
| 15:00 | Rijnsburgse Boys | - | SVV Scheveningen | 0:2 (0:1) | ||
| 15:30 | HHC Hardenberg | - | De Treffers | 2:1 (2:0) | ||
| 15:30 | IJsselmeervogels | - | TEC VV | 3:0 (1:0) | ||
| 15:30 | Sparta Rotterdam (J) | - | SV Spakenburg | 0:6 (0:2) | ||
| 15:30 | VV Katwijk | - | Koninklijke HFC | 0:1 (0:0) |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
VV Katwijk | 16 | 12 | 2 | 2 | 37:14 | 23 | 38 |
| 2 |
|
Amsterdamsche FC | 16 | 9 | 4 | 3 | 33:17 | 16 | 31 |
| 3 |
|
Koninklijke HFC | 16 | 8 | 4 | 4 | 24:18 | 6 | 28 |
| 4 |
|
HHC Hardenberg | 16 | 8 | 4 | 4 | 21:16 | 5 | 28 |
| 5 |
|
De Treffers | 16 | 8 | 3 | 5 | 21:17 | 4 | 27 |
| 6 |
|
Sparta Rotterdam (J) | 16 | 8 | 2 | 6 | 30:30 | 0 | 26 |
| 7 |
|
Rijnsburgse Boys | 16 | 7 | 2 | 7 | 29:23 | 6 | 23 |
| 8 |
|
Quick Boys | 16 | 6 | 5 | 5 | 23:19 | 4 | 23 |
| 9 |
|
VV Noordwijk | 16 | 7 | 2 | 7 | 21:24 | -3 | 23 |
| 10 |
|
SVV Scheveningen | 16 | 5 | 6 | 5 | 18:24 | -6 | 21 |
| 11 |
|
Excelsior Maassluis | 16 | 6 | 2 | 8 | 22:25 | -3 | 20 |
| 12 |
|
SV Spakenburg | 16 | 5 | 4 | 7 | 33:32 | 1 | 19 |
| 13 |
|
TEC VV | 16 | 5 | 4 | 7 | 19:33 | -14 | 19 |
| 14 |
|
Jong FC Volendam | 16 | 5 | 3 | 8 | 33:32 | 1 | 18 |
| 15 |
|
IJsselmeervogels | 16 | 5 | 2 | 9 | 20:27 | -7 | 17 |
| 16 |
|
ASWH Ido-Ambacht | 16 | 4 | 3 | 9 | 21:26 | -5 | 15 |
| 17 |
|
Kozakken Boys | 16 | 3 | 6 | 7 | 19:28 | -9 | 15 |
| 18 |
|
GVVV | 16 | 2 | 4 | 10 | 10:29 | -19 | 10 |
| Relégation | |
| Relégation | |
| Relégation |
