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| 20.01.2023 | 20:00 | TOP Oss | - | NAC Breda | 1:2 (0:2) | |
| 20:00 | PEC Zwolle | - | VVV-Venlo | 2:0 (0:0) | ||
| 20:00 | FC Den Bosch | - | Jong PSV | 1:0 (0:0) | ||
| 20:00 | Almere City FC | - | De Graafschap | 2:2 (1:1) | ||
| 21.01.2023 | 16:30 | FC Dordrecht | - | Telstar | 0:0 (0:0) | |
| 22.01.2023 | 12:15 | ADO Den Haag | - | FC Utrecht (J) | 1:1 (1:0) | |
| 23.01.2023 | 20:00 | AZ Alkmaar (J) | - | Helmond Sport | 1:1 (0:0) | |
| 20:00 | Jong Ajax | - | Roda JC Kerkrade | 1:2 (1:2) | ||
| 06.02.2023 | 20:00 | Willem II | - | FC Eindhoven | 3:0 (1:0) | |
| 13.02.2023 | 20:00 | MVV | - | Heracles Almelo | 0:2 (0:1) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
PEC Zwolle | 21 | 16 | 2 | 3 | 51:22 | 29 | 50 |
| 2 |
|
Heracles Almelo | 21 | 15 | 2 | 4 | 58:26 | 32 | 47 |
| 3 |
|
FC Eindhoven | 21 | 10 | 6 | 5 | 35:28 | 7 | 36 |
| 4 |
|
Almere City FC | 21 | 11 | 3 | 7 | 33:27 | 6 | 36 |
| 5 |
|
VVV-Venlo | 21 | 10 | 5 | 6 | 31:30 | 1 | 35 |
| 6 |
|
MVV | 21 | 10 | 4 | 7 | 37:35 | 2 | 34 |
| 7 |
|
Willem II | 21 | 9 | 6 | 6 | 31:22 | 9 | 33 |
| 8 |
|
AZ Alkmaar (J) | 21 | 9 | 5 | 7 | 34:26 | 8 | 32 |
| 9 |
|
Telstar | 21 | 7 | 8 | 6 | 23:28 | -5 | 29 |
| 10 |
|
NAC Breda | 21 | 8 | 4 | 9 | 29:35 | -6 | 28 |
| 11 |
|
Roda JC Kerkrade | 21 | 8 | 4 | 9 | 31:30 | 1 | 28 |
| 12 |
|
De Graafschap | 21 | 7 | 5 | 9 | 33:34 | -1 | 26 |
| 13 |
|
Jong PSV | 21 | 6 | 6 | 9 | 32:34 | -2 | 24 |
| 14 |
|
ADO Den Haag | 21 | 6 | 6 | 9 | 24:32 | -8 | 24 |
| 15 |
|
Jong Ajax | 21 | 5 | 8 | 8 | 35:38 | -3 | 23 |
| 16 |
|
FC Dordrecht | 21 | 6 | 5 | 10 | 24:36 | -12 | 23 |
| 17 |
|
FC Den Bosch | 21 | 7 | 1 | 13 | 29:41 | -12 | 22 |
| 18 |
|
Helmond Sport | 21 | 6 | 3 | 12 | 18:35 | -17 | 21 |
| 19 |
|
TOP Oss | 21 | 5 | 3 | 13 | 21:36 | -15 | 18 |
| 20 |
|
FC Utrecht (J) | 21 | 4 | 4 | 13 | 20:34 | -14 | 16 |
| Promotion | |
| Play-off |
