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| 19.02.2016 | 20:00 | FC Dordrecht | - | MVV | 1:0 (0:0) | |
| 20:00 | NAC Breda | - | Fortuna Sittard | 5:0 (3:0) | ||
| 20:00 | Jong PSV | - | FC Emmen | 0:0 (0:0) | ||
| 20:00 | Go Ahead Eagles | - | RKC Waalwijk | 1:0 (1:0) | ||
| 20:00 | FC Den Bosch | - | FC Eindhoven | 3:1 (2:1) | ||
| 20:00 | FC Oss | - | Jong Ajax | 1:2 (0:1) | ||
| 20:00 | Almere City FC | - | FC Volendam | 2:2 (1:2) | ||
| 20:00 | Telstar | - | Sparta Rotterdam | 1:3 (1:2) | ||
| 20:00 | Helmond Sport | - | VVV-Venlo | 1:4 (1:2) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Sparta Rotterdam | 25 | 19 | 4 | 2 | 64:25 | 39 | 61 |
| 2 |
|
VVV-Venlo | 26 | 16 | 4 | 6 | 60:23 | 37 | 52 |
| 3 |
|
NAC Breda | 26 | 15 | 4 | 7 | 54:24 | 30 | 49 |
| 4 |
|
FC Eindhoven | 26 | 14 | 5 | 7 | 43:32 | 11 | 47 |
| 5 |
|
FC Volendam | 26 | 11 | 8 | 7 | 43:30 | 13 | 41 |
| 6 |
|
FC Emmen | 26 | 12 | 5 | 9 | 41:36 | 5 | 41 |
| 7 |
|
Go Ahead Eagles | 25 | 12 | 3 | 10 | 38:31 | 7 | 39 |
| 8 |
|
Jong Ajax | 25 | 9 | 7 | 9 | 42:44 | -2 | 34 |
| 9 |
|
Telstar | 26 | 9 | 5 | 12 | 42:43 | -1 | 32 |
| 10 |
|
FC Dordrecht | 26 | 9 | 5 | 12 | 34:45 | -11 | 32 |
| 11 |
|
Jong PSV | 25 | 8 | 8 | 9 | 34:46 | -12 | 32 |
| 12 |
|
FC Den Bosch | 26 | 7 | 10 | 9 | 31:33 | -2 | 31 |
| 13 |
|
Helmond Sport | 26 | 8 | 7 | 11 | 39:43 | -4 | 31 |
| 14 |
|
Achilles'29 | 25 | 8 | 7 | 10 | 29:37 | -8 | 31 |
| 15 |
|
MVV | 26 | 8 | 6 | 12 | 37:50 | -13 | 30 |
| 16 |
|
FC Oss | 25 | 6 | 7 | 12 | 31:47 | -16 | 25 |
| 17 |
|
Fortuna Sittard | 26 | 7 | 4 | 15 | 28:61 | -33 | 25 |
| 18 |
|
Almere City FC | 25 | 5 | 7 | 13 | 36:52 | -16 | 22 |
| 19 |
|
RKC Waalwijk | 25 | 4 | 6 | 15 | 24:48 | -24 | 18 |
| Promotion | |
| Play-off | |
| Play-off | |
| Play-off |
