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| 13.11.2021 | 14:30 | AFC Ajax Zaterdag | - | FC Lisse | 3:0 (3:0) | |
| 14:30 | VV Staphorst | - | VVOG Harderwijk | 4:3 (1:2) | ||
| 14:30 | Excelsior '31 | - | Harkemase Boys | 3:2 (1:1) | ||
| 14:30 | DVS'33 | - | ACV Assen | 1:0 (1:0) | ||
| 15:00 | Ter Leede | - | VV DOVO Veenendaal | 1:1 (1:1) | ||
| 12.02.2022 | 14:30 | VV GOES | - | Sparta Nijkerk | 1:3 (1:1) | |
| 15:00 | Sportlust '46 | - | ODIN '59 | 3:1 (1:1) | ||
| 08.03.2022 | 20:00 | BVV Barendrecht | - | SteDoCo | 2:2 (0:1) | |
| 20:00 | VV Sint Bavo | - | HSV Hoek | 1:3 (1:2) |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Sportlust '46 | 12 | 7 | 2 | 3 | 27:17 | 10 | 23 |
| 2 |
|
Excelsior '31 | 12 | 7 | 2 | 3 | 25:15 | 10 | 23 |
| 3 |
|
Sparta Nijkerk | 12 | 7 | 2 | 3 | 22:12 | 10 | 23 |
| 4 |
|
FC Lisse | 12 | 7 | 2 | 3 | 23:14 | 9 | 23 |
| 5 |
|
Harkemase Boys | 12 | 6 | 3 | 3 | 28:20 | 8 | 21 |
| 6 |
|
DVS'33 | 12 | 6 | 2 | 4 | 18:11 | 7 | 20 |
| 7 |
|
VV Staphorst | 12 | 5 | 4 | 3 | 18:15 | 3 | 19 |
| 8 |
|
HSV Hoek | 12 | 5 | 3 | 4 | 21:18 | 3 | 18 |
| 9 |
|
BVV Barendrecht | 12 | 4 | 5 | 3 | 24:20 | 4 | 17 |
| 10 |
|
SteDoCo | 12 | 4 | 4 | 4 | 18:16 | 2 | 16 |
| 11 |
|
AFC Ajax Zaterdag | 12 | 5 | 1 | 6 | 14:21 | -7 | 16 |
| 12 |
|
Ter Leede | 12 | 4 | 3 | 5 | 13:20 | -7 | 15 |
| 13 |
|
ACV Assen | 12 | 4 | 2 | 6 | 17:17 | 0 | 14 |
| 14 |
|
VV DOVO Veenendaal | 12 | 2 | 4 | 6 | 11:20 | -9 | 10 |
| 15 |
|
VV Sint Bavo | 12 | 2 | 4 | 6 | 14:24 | -10 | 10 |
| 16 |
|
VVOG Harderwijk | 12 | 2 | 4 | 6 | 20:32 | -12 | 10 |
| 17 |
|
VV GOES | 12 | 1 | 6 | 5 | 16:24 | -8 | 9 |
| 18 |
|
ODIN '59 | 12 | 2 | 3 | 7 | 12:25 | -13 | 9 |
| Promotion | |
| Relégation | |
| Relégation |
