 |
 |
|
|
| 05.02.2022 | 18:00 | CF América | - | Atlético San Luis | 3:1 (0:0) | |
| 18:15 | Club Necaxa | - | CF Pachuca | 0:1 (0:1) | ||
| 21:45 | Club Tijuana | - | Pumas UNAM | 2:0 (0:0) | ||
| 06.02.2022 | 18:00 | UANL Tigres | - | Mazatlán FC | 3:3 (2:2) | |
| 18:30 | Gallos Blancos | - | Puebla FC | 3:1 (2:1) | ||
| 18:30 | Atlas Guadalajara | - | Santos Laguna | 2:1 (0:0) | ||
| 18:30 | Deportivo Toluca | - | CF Monterrey | 3:0 (2:0) | ||
| 07.02.2022 | 18:30 | Club León | - | Cruz Azul | 1:0 (1:0) | |
| 29.03.2022 | 20:30 | FC Juárez | - | Deportivo Guadalajara | 1:1 (1:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Atlas Guadalajara | 4 | 3 | 1 | 0 | 4:1 | 3 | 21 |
| 2 |
|
CF América | 4 | 3 | 1 | 0 | 7:1 | 6 | 20 |
| 3 |
|
CF Monterrey | 4 | 3 | 0 | 1 | 8:6 | 2 | 20 |
| 4 |
|
Club León | 4 | 3 | 0 | 1 | 7:4 | 3 | 16 |
| 5 |
|
UANL Tigres | 4 | 2 | 1 | 1 | 8:9 | -1 | 16 |
| 6 |
|
Deportivo Guadalajara | 4 | 2 | 1 | 1 | 8:6 | 2 | 15 |
| 7 |
|
Club Tijuana | 4 | 1 | 1 | 2 | 6:6 | 0 | 15 |
| 8 |
|
Cruz Azul | 4 | 2 | 0 | 2 | 4:4 | 0 | 15 |
| 9 |
|
Santos Laguna | 4 | 1 | 1 | 2 | 9:6 | 3 | 13 |
| 10 |
|
Deportivo Toluca | 4 | 1 | 2 | 1 | 5:3 | 2 | 13 |
| 11 |
|
CF Pachuca | 4 | 2 | 0 | 2 | 7:7 | 0 | 13 |
| 12 |
|
Pumas UNAM | 4 | 2 | 0 | 2 | 5:6 | -1 | 13 |
| 13 |
|
FC Juárez | 4 | 1 | 2 | 1 | 7:6 | 1 | 12 |
| 14 |
|
Mazatlán FC | 4 | 0 | 2 | 2 | 4:10 | -6 | 12 |
| 15 |
|
Atlético San Luis | 4 | 1 | 1 | 2 | 3:5 | -2 | 10 |
| 16 |
|
Gallos Blancos | 4 | 1 | 0 | 3 | 5:8 | -3 | 10 |
| 17 |
|
Puebla FC | 4 | 0 | 1 | 3 | 2:6 | -4 | 10 |
| 18 |
|
Club Necaxa | 4 | 1 | 0 | 3 | 6:11 | -5 | 10 |
| Play-off |
