 |
 |
|
|
| 14.01.2022 | 18:15 | Club Necaxa | - | CF Monterrey | 1:4 (0:1) | |
| 18:30 | Gallos Blancos | - | Pumas UNAM | 0:3 (0:0) | ||
| 15.01.2022 | 18:00 | UANL Tigres | - | Puebla FC | 1:0 (0:0) | |
| 18:15 | Cruz Azul | - | FC Juárez | 1:0 (0:0) | ||
| 18:30 | Atlas Guadalajara | - | Atlético San Luis | 1:0 (0:0) | ||
| 21:45 | Club Tijuana | - | Club León | 1:2 (1:1) | ||
| 16.01.2022 | 16:00 | CF Pachuca | - | Deportivo Guadalajara | 4:2 (3:0) | |
| 18:30 | Deportivo Toluca | - | Santos Laguna | 2:2 (1:1) | ||
| 16.02.2022 | 19:30 | Mazatlán FC | - | CF América | 0:3 (0:2) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CF Monterrey | 2 | 2 | 0 | 0 | 7:3 | 4 | 17 |
| 2 |
|
Atlas Guadalajara | 2 | 2 | 0 | 0 | 2:0 | 2 | 17 |
| 3 |
|
CF América | 2 | 2 | 0 | 0 | 4:0 | 4 | 16 |
| 4 |
|
Cruz Azul | 2 | 2 | 0 | 0 | 4:2 | 2 | 15 |
| 5 |
|
Santos Laguna | 2 | 1 | 1 | 0 | 7:2 | 5 | 13 |
| 6 |
|
Pumas UNAM | 2 | 2 | 0 | 0 | 4:0 | 4 | 13 |
| 7 |
|
UANL Tigres | 2 | 1 | 0 | 1 | 1:5 | -4 | 12 |
| 8 |
|
Deportivo Guadalajara | 2 | 1 | 0 | 1 | 6:5 | 1 | 11 |
| 9 |
|
Club Tijuana | 2 | 0 | 0 | 2 | 3:5 | -2 | 11 |
| 10 |
|
FC Juárez | 2 | 1 | 0 | 1 | 5:4 | 1 | 10 |
| 11 |
|
CF Pachuca | 2 | 1 | 0 | 1 | 4:3 | 1 | 10 |
| 12 |
|
Club León | 2 | 1 | 0 | 1 | 2:2 | 0 | 10 |
| 13 |
|
Mazatlán FC | 2 | 0 | 0 | 2 | 1:7 | -6 | 10 |
| 14 |
|
Atlético San Luis | 2 | 1 | 0 | 1 | 1:1 | 0 | 9 |
| 15 |
|
Deportivo Toluca | 2 | 0 | 1 | 1 | 2:3 | -1 | 9 |
| 16 |
|
Puebla FC | 2 | 0 | 0 | 2 | 0:2 | -2 | 9 |
| 17 |
|
Gallos Blancos | 2 | 0 | 0 | 2 | 2:6 | -4 | 7 |
| 18 |
|
Club Necaxa | 2 | 0 | 0 | 2 | 4:9 | -5 | 7 |
| Play-off |
