 |
 |
|
| 04.09.2021 | 16:00 | UANL Tigres | - | Atlas Guadalajara | 2:1 (0:1) | |
| 16:00 | Cruz Azul | - | FC Juárez | 1:0 (0:0) | ||
| 16:00 | Gallos Blancos | - | CF Pachuca | 1:1 (1:0) | ||
| 16:00 | Santos Laguna | - | Club León | 1:0 (0:0) | ||
| 16:00 | CF Monterrey | - | Club Necaxa | 1:0 (0:0) | ||
| 17:00 | Pumas UNAM | - | Puebla FC | 3:0 (0:0) | ||
| 18:00 | Mazatlán FC | - | Deportivo Guadalajara | 1:7 (0:2) | ||
| 19:00 | Club Tijuana | - | CF América | 2:1 (1:1) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Santos Laguna | 6 | 4 | 2 | 0 | 15:6 | 9 | 14 |
| 2 |
|
Pumas UNAM | 7 | 4 | 2 | 1 | 13:8 | 5 | 14 |
| 3 |
|
Deportivo Guadalajara | 6 | 4 | 1 | 1 | 21:6 | 15 | 13 |
| 4 |
|
Club Necaxa | 7 | 4 | 1 | 2 | 11:6 | 5 | 13 |
| 5 |
|
Deportivo Toluca | 6 | 4 | 1 | 1 | 12:9 | 3 | 13 |
| 6 |
|
CF Pachuca | 6 | 4 | 1 | 1 | 8:5 | 3 | 13 |
| 7 |
|
CF Monterrey | 7 | 3 | 2 | 2 | 10:10 | 0 | 11 |
| 8 |
|
Cruz Azul | 6 | 3 | 1 | 2 | 7:6 | 1 | 10 |
| 9 |
|
Atlas Guadalajara | 6 | 3 | 0 | 3 | 19:13 | 6 | 9 |
| 10 |
|
Mazatlán FC | 6 | 3 | 0 | 3 | 12:18 | -6 | 9 |
| 11 |
|
Gallos Blancos | 7 | 2 | 2 | 3 | 9:9 | 0 | 8 |
| 12 |
|
UANL Tigres | 6 | 2 | 1 | 3 | 9:11 | -2 | 7 |
| 13 |
|
Club Tijuana | 6 | 2 | 1 | 3 | 6:9 | -3 | 7 |
| 14 |
|
CF América | 6 | 2 | 0 | 4 | 8:8 | 0 | 6 |
| 15 |
|
Puebla FC | 6 | 2 | 0 | 4 | 9:12 | -3 | 6 |
| 16 |
|
Club León | 6 | 1 | 1 | 4 | 6:14 | -8 | 4 |
| 17 |
|
FC Juárez | 6 | 0 | 2 | 4 | 5:11 | -6 | 2 |
| 18 |
|
Atlético San Luis | 6 | 0 | 0 | 6 | 5:24 | -19 | 0 |
| Play-off |
