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| H (Match allé) | Alebrijes de Oaxaca II | - | Aguacateros CDU | 1:0 (1:0) | ||
| R (match retour) | Aguacateros CDU | - | Alebrijes de Oaxaca II | 4:1 (2:1) | ||
| H (Match allé): 15.05.2022 01:00 | R (match retour): 21.05.2022 23:00 | vainqueur: Aguacateros CDU | ||||
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| H (Match allé) | Alebrijes de Oaxaca II | - | Aguacateros CDU | 1:0 (1:0) | ||
| R (match retour) | Aguacateros CDU | - | Alebrijes de Oaxaca II | 4:1 (2:1) | ||
| H (Match allé): 15.05.2022 01:00 | R (match retour): 21.05.2022 23:00 | vainqueur: Aguacateros CDU | ||||
