 |
 |
|
|
| 16.03.2022 | 22:45 | CF América | - | Gallos Blancos | 4:1 (0:1) | |
| 17.03.2022 | 03:00 | FC Juárez | - | Mazatlán FC | 1:1 (0:0) | |
| 17:00 | Club León | - | Puebla FC | 2:0 (0:0) | ||
| 19:00 | Club Necaxa | - | Deportivo Toluca | 2:2 (0:1) | ||
| 18.03.2022 | 02:00 | Santos Laguna | - | CF Pachuca | 0:1 (0:0) | |
| 02:00 | UANL Tigres | - | Cruz Azul | 4:0 (0:0) | ||
| 04:00 | CF Monterrey | - | Atlético San Luis | 1:0 (1:0) | ||
| 17:30 | Deportivo Guadalajara | - | Club Tijuana | 3:0 (2:0) | ||
| 19.03.2022 | 00:00 | Pumas UNAM | - | Atlas Guadalajara | 0:0 (0:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CF Monterrey | 11 | 11 | 0 | 0 | 40:8 | 32 | 33 |
| 2 |
|
CF América | 11 | 8 | 1 | 2 | 27:9 | 18 | 25 |
| 3 |
|
UANL Tigres | 11 | 7 | 4 | 0 | 25:9 | 16 | 25 |
| 4 |
|
Deportivo Guadalajara | 11 | 7 | 4 | 0 | 19:5 | 14 | 25 |
| 5 |
|
CF Pachuca | 11 | 7 | 1 | 3 | 18:10 | 8 | 22 |
| 6 |
|
Atlas Guadalajara | 11 | 4 | 5 | 2 | 17:16 | 1 | 17 |
| 7 |
|
Pumas UNAM | 11 | 3 | 4 | 4 | 10:10 | 0 | 13 |
| 8 |
|
Deportivo Toluca | 11 | 3 | 4 | 4 | 18:20 | -2 | 13 |
| 9 |
|
Club León | 11 | 3 | 3 | 5 | 13:21 | -8 | 12 |
| 10 |
|
Gallos Blancos | 11 | 3 | 3 | 5 | 10:19 | -9 | 12 |
| 11 |
|
Atlético San Luis | 11 | 2 | 5 | 4 | 11:15 | -4 | 11 |
| 12 |
|
Club Tijuana | 11 | 1 | 7 | 3 | 13:22 | -9 | 10 |
| 13 |
|
Mazatlán FC | 11 | 2 | 4 | 5 | 9:18 | -9 | 10 |
|
Puebla FC | 11 | 3 | 1 | 7 | 9:18 | -9 | 10 | |
| 15 |
|
Club Necaxa | 11 | 2 | 4 | 5 | 12:22 | -10 | 10 |
| 16 |
|
Cruz Azul | 11 | 2 | 3 | 6 | 11:20 | -9 | 9 |
| 17 |
|
Santos Laguna | 11 | 2 | 1 | 8 | 7:19 | -12 | 7 |
| 18 |
|
FC Juárez | 11 | 1 | 2 | 8 | 10:18 | -8 | 5 |
| Play-off |
