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| 21.05.2022 | 06:00 | Sanfrecce Hiroshima | - | Kyoto Sanga FC | 3:1 (2:1) | |
| 07:00 | Shimizu S-Pulse | - | Nagoya Grampus | 1:2 (0:1) | ||
| 07:00 | Cerezo Osaka | - | Gamba Osaka | 3:1 (0:1) | ||
| 08:00 | FC Tokyo | - | Kashiwa Reysol | 0:0 (0:0) | ||
| 08:00 | Shonan Bellmare | - | Vissel Kobe | 2:1 (1:0) | ||
| 10:00 | Urawa Red Diamonds | - | Kashima Antlers | 1:1 (1:1) | ||
| 10:00 | Sagan Tosu | - | Kawasaki Frontale | 0:0 (0:0) | ||
| 12:00 | Avispa Fukuoka | - | Yokohama F. Marinos | 1:0 (0:0) | ||
| 22.05.2022 | 08:00 | Júbilo Iwata | - | Hokkaido Consadole Sapporo | 1:2 (1:1) |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Kawasaki Frontale | 14 | 9 | 3 | 2 | 20:12 | 8 | 30 |
| 2 |
|
Kashima Antlers | 14 | 9 | 2 | 3 | 22:14 | 8 | 29 |
| 3 |
|
Yokohama F. Marinos | 14 | 7 | 4 | 3 | 26:17 | 9 | 25 |
| 4 |
|
Sanfrecce Hiroshima | 14 | 5 | 6 | 3 | 18:13 | 5 | 21 |
| 5 |
|
Kashiwa Reysol | 14 | 6 | 3 | 5 | 13:12 | 1 | 21 |
| 6 |
|
Sagan Tosu | 14 | 4 | 8 | 2 | 15:11 | 4 | 20 |
| 7 |
|
Cerezo Osaka | 14 | 5 | 5 | 4 | 19:16 | 3 | 20 |
| 8 |
|
Hokkaido Consadole Sapporo | 14 | 4 | 8 | 2 | 13:16 | -3 | 20 |
| 9 |
|
FC Tokyo | 14 | 5 | 4 | 5 | 12:13 | -1 | 19 |
| 10 |
|
Avispa Fukuoka | 14 | 4 | 6 | 4 | 11:9 | 2 | 18 |
| 11 |
|
Kyoto Sanga FC | 14 | 4 | 5 | 5 | 15:16 | -1 | 17 |
| 12 |
|
Gamba Osaka | 14 | 4 | 5 | 5 | 16:18 | -2 | 17 |
| 13 |
|
Nagoya Grampus | 14 | 4 | 5 | 5 | 13:15 | -2 | 17 |
| 14 |
|
Urawa Red Diamonds | 14 | 2 | 8 | 4 | 15:14 | 1 | 14 |
| 15 |
|
Júbilo Iwata | 14 | 3 | 5 | 6 | 18:23 | -5 | 14 |
| 16 |
|
Shimizu S-Pulse | 14 | 2 | 7 | 5 | 14:18 | -4 | 13 |
| 17 |
|
Shonan Bellmare | 14 | 2 | 4 | 8 | 9:21 | -12 | 10 |
| 18 |
|
Vissel Kobe | 14 | 1 | 4 | 9 | 10:21 | -11 | 7 |
| Champions League | |
| Champions League Quali. | |
| Relégation | |
| Relégation |
