 |
 |
|
|
| 12.02.2022 | 18:30 | Asteras Tripolis | - | Ionikos Nikea | 2:3 (1:0) | |
| 18:30 | Apollon Smyrnis | - | Panetolikos | 0:0 (0:0) | ||
| 13.02.2022 | 14:00 | OFI Heraklion | - | Volos NFC | 2:1 (2:0) | |
| 14:30 | Panathinaikos | - | Lamia | 2:0 (1:0) | ||
| 16:15 | PAOK Saloniki | - | Atromitos | 1:0 (0:0) | ||
| 18:30 | Olympiakos Piraeus | - | AEK Athen | 1:0 (0:0) | ||
| 14.02.2022 | 18:30 | PAS Giannina | - | Aris Saloniki | 2:0 (0:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Olympiakos Piraeus | 23 | 18 | 5 | 0 | 43:12 | 31 | 59 |
| 2 |
|
PAOK Saloniki | 23 | 15 | 3 | 5 | 47:23 | 24 | 48 |
| 3 |
|
AEK Athen | 23 | 12 | 4 | 7 | 38:24 | 14 | 40 |
| 4 |
|
Aris Saloniki | 23 | 11 | 5 | 7 | 24:20 | 4 | 38 |
| 5 |
|
Panathinaikos | 23 | 11 | 3 | 9 | 36:20 | 16 | 36 |
| 6 |
|
PAS Giannina | 23 | 10 | 6 | 7 | 27:22 | 5 | 36 |
| 7 |
|
Asteras Tripolis | 23 | 10 | 5 | 8 | 26:23 | 3 | 35 |
| 8 |
|
OFI Heraklion | 23 | 8 | 9 | 6 | 31:30 | 1 | 33 |
| 9 |
|
Volos NFC | 23 | 8 | 4 | 11 | 35:41 | -6 | 28 |
| 10 |
|
Panetolikos | 23 | 7 | 4 | 12 | 24:38 | -14 | 25 |
| 11 |
|
Ionikos Nikea | 23 | 6 | 6 | 11 | 24:31 | -7 | 24 |
| 12 |
|
Lamia | 23 | 4 | 6 | 13 | 18:32 | -14 | 18 |
| 13 |
|
Atromitos | 23 | 4 | 5 | 14 | 23:45 | -22 | 17 |
| 14 |
|
Apollon Smyrnis | 23 | 1 | 7 | 15 | 7:42 | -35 | 10 |
| Play-off | |
| Relégation |
