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| 09.04.2022 | 16:00 | AS Monaco (CFA) | - | Étoile FC | 0:1 (0:1) | |
| 16:00 | Olympique Lyon (CFA) | - | Marignane Gignac FC | 3:1 (1:1) | ||
| 18:00 | Hyères FC | - | Aubagne FC | 1:1 (0:1) | ||
| 18:00 | FC Martigues | - | AS Saint-Priest | 1:0 (0:0) | ||
| 18:00 | GFA Rumilly Vallières | - | SC Toulon | 1:0 (0:0) | ||
| 18:00 | RC Grasse | - | Olympique Marseille (CFA) | 3:1 (2:0) | ||
| 18:00 | Louhans-Cuiseaux | - | Jura Sud | 6:1 (3:1) | ||
| 18:00 | Lyon-La Duchère | - | GOAL FC | 1:0 (0:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
GOAL FC | 24 | 13 | 8 | 3 | 41:17 | 24 | 47 |
| 2 |
|
FC Martigues | 24 | 12 | 8 | 4 | 33:23 | 10 | 44 |
| 3 |
|
RC Grasse | 24 | 11 | 8 | 5 | 29:22 | 7 | 41 |
| 4 |
|
Étoile FC | 24 | 10 | 7 | 7 | 27:21 | 6 | 37 |
| 5 |
|
Louhans-Cuiseaux | 24 | 9 | 9 | 6 | 33:22 | 11 | 36 |
| 6 |
|
Aubagne FC | 24 | 9 | 9 | 6 | 31:23 | 8 | 36 |
| 7 |
|
Marignane Gignac FC | 24 | 10 | 5 | 9 | 27:24 | 3 | 35 |
| 8 |
|
Olympique Lyon (CFA) | 24 | 9 | 7 | 8 | 25:30 | -5 | 34 |
| 9 |
|
Jura Sud | 24 | 9 | 5 | 10 | 32:37 | -5 | 32 |
| 10 |
|
Hyères FC | 24 | 7 | 10 | 7 | 27:28 | -1 | 31 |
| 11 |
|
SC Toulon | 24 | 6 | 9 | 9 | 23:24 | -1 | 27 |
| 12 |
|
Lyon-La Duchère | 24 | 6 | 8 | 10 | 26:32 | -6 | 26 |
| 13 |
|
AS Saint-Priest | 24 | 7 | 4 | 13 | 27:35 | -8 | 25 |
| 14 |
|
AS Monaco (CFA) | 24 | 6 | 7 | 11 | 24:32 | -8 | 25 |
| 15 |
|
GFA Rumilly Vallières | 24 | 6 | 7 | 11 | 19:30 | -11 | 25 |
| 16 |
|
Olympique Marseille (CFA) | 24 | 5 | 3 | 16 | 22:46 | -24 | 18 |
| Promotion | |
| Relégation |
