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| 04.12.2021 | 18:00 | AS Vitré | - | Stade Plabennec | 1:0 (1:0) | |
| 18:00 | C'Chartres Football | - | SM Caen (CFA) | 4:0 (2:0) | ||
| 18:00 | US Granvillaise | - | FC Lorient (CFA) | 0:0 (0:0) | ||
| 18:00 | FC Rouen 1899 | - | St-Pryvé St-Hilaire | 1:1 (1:0) | ||
| 18:00 | SO Romorantin | - | Blois Foot 41 | 1:1 (1:1) | ||
| 18:00 | FC Versailles | - | US Saint-Malo | 1:0 (1:0) | ||
| 18:00 | Châteaubriant Voltigeurs | - | AS Poissy | 2:1 (2:0) | ||
| 26.01.2022 | 18:00 | Vannes OC | - | EA Guingamp (CFA) | 2:0 (1:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Lorient (CFA) | 13 | 8 | 3 | 2 | 19:9 | 10 | 27 |
| 2 |
|
FC Versailles | 13 | 7 | 5 | 1 | 17:7 | 10 | 26 |
| 3 |
|
Châteaubriant Voltigeurs | 13 | 7 | 3 | 3 | 20:12 | 8 | 24 |
| 4 |
|
St-Pryvé St-Hilaire | 13 | 6 | 3 | 4 | 14:11 | 3 | 21 |
| 5 |
|
C'Chartres Football | 13 | 6 | 2 | 5 | 22:15 | 7 | 20 |
| 6 |
|
Blois Foot 41 | 13 | 5 | 5 | 3 | 18:20 | -2 | 20 |
| 7 |
|
Vannes OC | 13 | 4 | 6 | 3 | 15:12 | 3 | 18 |
| 8 |
|
FC Rouen 1899 | 13 | 4 | 5 | 4 | 15:13 | 2 | 17 |
| 9 |
|
AS Poissy | 13 | 3 | 7 | 3 | 13:10 | 3 | 16 |
| 10 |
|
EA Guingamp (CFA) | 13 | 4 | 4 | 5 | 17:19 | -2 | 16 |
| 11 |
|
US Granvillaise | 13 | 3 | 7 | 3 | 12:12 | 0 | 16 |
| 12 |
|
SM Caen (CFA) | 13 | 4 | 4 | 5 | 9:16 | -7 | 16 |
| 13 |
|
SO Romorantin | 13 | 4 | 4 | 5 | 13:16 | -3 | 16 |
| 14 |
|
US Saint-Malo | 13 | 3 | 2 | 8 | 8:19 | -11 | 11 |
| 15 |
|
Stade Plabennec | 13 | 2 | 3 | 8 | 9:17 | -8 | 9 |
| 16 |
|
AS Vitré | 13 | 1 | 3 | 9 | 5:18 | -13 | 6 |
| Promotion | |
| Relégation |
