 |
 |
|
| 16.04.2022 | 17:00 | Levante UD B | - | CD Marchamalo | 1:0 (0:0) | |
| 18:00 | UD Alzira | - | Mar Menor CF | 1:0 (0:0) | ||
| 17.04.2022 | 12:00 | Hércules CF | - | UD Melilla | 1:1 (0:1) | |
| 12:00 | UD Socuéllamos | - | CF Intercity | 2:1 (1:0) | ||
| 18:00 | CD El Ejido 2012 | - | CD Toledo | 1:2 (0:2) | ||
| 18:00 | CD Eldense | - | Águilas FC | 0:1 (0:0) | ||
| 18:00 | Real Murcia | - | CS Puertollano CF | 3:1 (2:0) | ||
| 18:00 | CA Pulpileño | - | Recreativo Granada | 0:3 (0:1) | ||
| 19:00 | CF La Nucía | - | Atlético Mancha Real | 1:1 (0:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CF Intercity | 30 | 16 | 11 | 3 | 37:15 | 22 | 59 |
| 2 |
|
CF La Nucía | 30 | 16 | 9 | 5 | 38:17 | 21 | 57 |
| 3 |
|
Real Murcia | 30 | 13 | 12 | 5 | 36:23 | 13 | 51 |
| 4 |
|
Hércules CF | 30 | 14 | 8 | 8 | 35:27 | 8 | 50 |
| 5 |
|
Mar Menor CF | 30 | 13 | 6 | 11 | 29:28 | 1 | 45 |
| 6 |
|
CD Eldense | 30 | 11 | 11 | 8 | 38:34 | 4 | 44 |
| 7 |
|
UD Alzira | 30 | 10 | 12 | 8 | 36:33 | 3 | 42 |
| 8 |
|
Recreativo Granada | 30 | 9 | 13 | 8 | 30:26 | 4 | 40 |
| 9 |
|
UD Melilla | 30 | 10 | 8 | 12 | 31:34 | -3 | 38 |
| 10 |
|
Levante UD B | 30 | 9 | 10 | 11 | 31:24 | 7 | 37 |
| 11 |
|
Águilas FC | 30 | 9 | 10 | 11 | 29:32 | -3 | 37 |
| 12 |
|
Atlético Mancha Real | 30 | 10 | 7 | 13 | 27:31 | -4 | 37 |
| 13 |
|
CD El Ejido 2012 | 30 | 10 | 7 | 13 | 24:29 | -5 | 37 |
| 14 |
|
UD Socuéllamos | 30 | 8 | 13 | 9 | 24:29 | -5 | 37 |
| 15 |
|
CA Pulpileño | 30 | 8 | 10 | 12 | 22:39 | -17 | 34 |
| 16 |
|
CD Marchamalo | 30 | 7 | 7 | 16 | 27:52 | -25 | 28 |
| 17 |
|
CD Toledo | 30 | 6 | 9 | 15 | 25:37 | -12 | 27 |
| 18 |
|
CS Puertollano CF | 30 | 7 | 5 | 18 | 32:41 | -9 | 26 |
| Promotion | |
| Play-off | |
| Relégation | |
| Relégation |
