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| 05.12.2021 | 12:00 | CE Andratx | - | CF Badalona | 1:0 (0:0) | |
| 12:00 | CE Europa | - | SD Formentera | 0:1 (0:1) | ||
| 12:00 | CD Ebro | - | SD Huesca B | 0:0 (0:0) | ||
| 12:00 | Espanyol Barcelona B | - | Peña Deportiva | 0:3 (0:2) | ||
| 12:00 | CD Ibiza | - | AE Prat | 0:1 (0:0) | ||
| 16:30 | CD Teruel | - | CD Brea | 0:1 (0:1) | ||
| 17:00 | Cerdanyola FC | - | Terrassa FC | 2:0 (0:0) | ||
| 17:00 | Lleida Esportiu | - | SD Ejea | 2:1 (2:0) | ||
| 17:00 | SD Tarazona | - | CD Numancia | 0:1 (0:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
SD Formentera | 14 | 7 | 4 | 3 | 16:11 | 5 | 25 |
| 2 |
|
CD Numancia | 14 | 7 | 3 | 4 | 17:12 | 5 | 24 |
| 3 |
|
CD Teruel | 14 | 6 | 6 | 2 | 17:14 | 3 | 24 |
| 4 |
|
Peña Deportiva | 14 | 6 | 5 | 3 | 21:14 | 7 | 23 |
| 5 |
|
Cerdanyola FC | 14 | 7 | 2 | 5 | 23:19 | 4 | 23 |
| 6 |
|
CE Andratx | 14 | 6 | 4 | 4 | 17:13 | 4 | 22 |
| 7 |
|
Espanyol Barcelona B | 14 | 6 | 3 | 5 | 19:18 | 1 | 21 |
| 8 |
|
Terrassa FC | 14 | 5 | 5 | 4 | 16:16 | 0 | 20 |
| 9 |
|
CD Ibiza | 14 | 4 | 7 | 3 | 16:12 | 4 | 19 |
| 10 |
|
CD Brea | 14 | 5 | 4 | 5 | 14:16 | -2 | 19 |
| 11 |
|
AE Prat | 14 | 5 | 4 | 5 | 14:13 | 1 | 19 |
| 12 |
|
SD Tarazona | 14 | 4 | 4 | 6 | 13:15 | -2 | 16 |
| 13 |
|
Lleida Esportiu | 14 | 4 | 4 | 6 | 14:19 | -5 | 16 |
| 14 |
|
CD Ebro | 14 | 3 | 6 | 5 | 12:13 | -1 | 15 |
| 15 |
|
SD Huesca B | 14 | 2 | 8 | 4 | 11:15 | -4 | 14 |
| 16 |
|
CE Europa | 14 | 3 | 5 | 6 | 15:20 | -5 | 14 |
| 17 |
|
CF Badalona | 14 | 3 | 5 | 6 | 9:14 | -5 | 14 |
| 18 |
|
SD Ejea | 14 | 1 | 5 | 8 | 11:21 | -10 | 8 |
| Promotion | |
| Play-off | |
| Relégation | |
| Relégation |
