H (Match allé) Marathón - Portland Timbers -:-
R (match retour) Portland Timbers - Marathón -:-
H (Match allé): 07.04.2021 00:00 R (match retour): 14.04.2021 02:00
H (Match allé) LD Alajuelense - Atlanta United FC -:-
R (match retour) Atlanta United FC - LD Alajuelense -:-
H (Match allé): 07.04.2021 02:00 R (match retour): 14.04.2021 00:00
H (Match allé) Arcahaie FC - Cruz Azul -:-
R (match retour) Cruz Azul - Arcahaie FC -:-
H (Match allé): 07.04.2021 04:00 R (match retour): 14.04.2021 04:00
H (Match allé) Deportivo Saprissa - Philadelphia Union -:-
R (match retour) Philadelphia Union - Deportivo Saprissa -:-
H (Match allé): 08.04.2021 00:00 R (match retour): 15.04.2021 02:00
H (Match allé) Club León - Forge / Toronto -:-
R (match retour) Forge / Toronto - Club León -:-
H (Match allé): 08.04.2021 02:00 R (match retour): 15.04.2021 00:00
H (Match allé) Olimpia - CF América -:-
R (match retour) CF América - Olimpia -:-
H (Match allé): 08.04.2021 04:00 R (match retour): 15.04.2021 02:00
H (Match allé) Real Estelí - Columbus Crew -:-
R (match retour) Columbus Crew - Real Estelí -:-
H (Match allé): 09.04.2021 02:00 R (match retour): 16.04.2021 02:00
H (Match allé) CD Pantoja - CF Monterrey -:-
R (match retour) CF Monterrey - CD Pantoja -:-
H (Match allé): 09.04.2021 04:00 R (match retour): 16.04.2021 04:00