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| H (Match allé) | Cascavel FC - PR | - | Maringá - PR | 0:1 (0:0) | ||
| R (match retour) | Maringá - PR | - | Cascavel FC - PR | 5:0 (3:0) | ||
| H (Match allé): 12.03.2022 22:30 | R (match retour): 20.03.2022 22:30 | vainqueur: Maringá - PR | ||||
| H (Match allé) | Londrina - PR | - | Athletico Paranaense | 1:0 (1:0) | ||
| R (match retour) | Athletico Paranaense | - | Londrina - PR | 4:2 (1:0, 2:1, 2:1) tab | ||
| H (Match allé): 13.03.2022 15:00 | R (match retour): 20.03.2022 20:00 | vainqueur: Athletico Paranaense | ||||
| H (Match allé) | Independente - PR | - | Operário Ferroviário - PR | 2:1 (2:0) | ||
| R (match retour) | Operário Ferroviário - PR | - | Independente - PR | 2:0 (1:0) | ||
| H (Match allé): 13.03.2022 19:30 | R (match retour): 19.03.2022 22:30 | vainqueur: Operário Ferroviário - PR | ||||
| H (Match allé) | Cianorte - PR | - | Coritiba - PR | 0:1 (0:1) | ||
| R (match retour) | Coritiba - PR | - | Cianorte - PR | 3:0 (1:0) | ||
| H (Match allé): 13.03.2022 22:30 | R (match retour): 19.03.2022 20:00 | vainqueur: Coritiba - PR | ||||
