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| H (Match allé) | Nacional - PB | - | Botafogo - PB | 3:1 (2:0) | ||
| R (match retour) | Botafogo - PB | - | Nacional - PB | 3:0 (1:0) | ||
| H (Match allé): 21.04.2022 01:15 | R (match retour): 27.04.2022 01:15 | vainqueur: Botafogo - PB | ||||
| H (Match allé) | Campinense - PB | - | Sousa - PB | 1:0 (1:0) | ||
| R (match retour) | Sousa - PB | - | Campinense - PB | 1:1 (0:1) | ||
| H (Match allé): 21.04.2022 01:15 | R (match retour): 28.04.2022 01:15 | vainqueur: Campinense - PB | ||||
