 |
 |
| Quarts de finale | ||||||
|---|---|---|---|---|---|---|
| 07.05.2021 | 17:00 | CF América | - | UANL Tigres | 0:4 (0:2) | |
| 19:00 | Pumas UNAM | - | CF Monterrey | 1:2 (0:2) | ||
| 23:00 | Deportivo Toluca | - | Deportivo Guadalajara | 0:1 (0:1) | ||
| 08.05.2021 | 01:30 | CF Pachuca | - | Atlas Guadalajara | 0:2 (0:1) | |
| 10.05.2021 | 23:00 | Atlas Guadalajara | - | CF Pachuca | 3:1 (1:0) | |
| 11.05.2021 | 01:00 | Deportivo Guadalajara | - | Deportivo Toluca | 3:0 (0:0) | |
| 03:00 | UANL Tigres | - | CF América | 2:0 (0:0) | ||
| 05:00 | CF Monterrey | - | Pumas UNAM | 2:1 (0:1) | ||
| Demi-finales | ||||||
| 15.05.2021 | 00:00 | Atlas Guadalajara | - | Deportivo Guadalajara | 0:0 (0:0) | |
| 04:05 | CF Monterrey | - | UANL Tigres | 2:2 (0:0) | ||
| 18.05.2021 | 02:00 | UANL Tigres | - | CF Monterrey | 4:1 (2:1) | |
| 04:00 | Deportivo Guadalajara | - | Atlas Guadalajara | 2:1 (0:0) | ||
| Finale | ||||||
| 25.05.2021 | 04:00 | Deportivo Guadalajara | - | UANL Tigres | 1:2 (0:1) | |
| 01.06.2021 | 02:00 | UANL Tigres | - | Deportivo Guadalajara | 5:3 (3:1) | |
