| 2. Journée | 20.08.2011 | Nacional | - | Defensor Sporting | 2:2 | ||||
| 3. Journée | 28.08.2011 | Defensor Sporting | - | Cerrito | 1:1 | ||||
| 4. Journée | 03.09.2011 | Peñarol | - | Defensor Sporting | 1:0 | ||||
| 5. Journée | 11.09.2011 | Defensor Sporting | - | Fénix | 0:1 |  |
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| 6. Journée | 18.09.2011 | Liverpool | - | Defensor Sporting | 2:3 | ||||
| 7. Journée | 24.09.2011 | Defensor Sporting | - | Rentistas | 1:0 | ||||
| 8. Journée | 02.10.2011 | Racing | - | Defensor Sporting | 0:3 | ||||
| 11. Journée | 04.11.2011 | Defensor Sporting | - | Danubio | 0:1 | ||||
| 10. Journée | 08.11.2011 | Montevideo Wanderers | - | Defensor Sporting | 0:2 | ||||
| 15. Journée | 02.12.2011 | Defensor Sporting | - | River Plate | 0:2 |  |
Uruguay