| 2. Journée | 25.08.2021 | Kaizer Chiefs | - | Baroka FC | 2:1 | ||||
| 3. Journée | 12.09.2021 | Mamelodi Sundowns | - | Kaizer Chiefs | 2:0 | ||||
| 6. Journée | 02.10.2021 | AmaZulu FC | - | Kaizer Chiefs | 1:1 | ||||
| 7. Journée | 16.10.2021 | Kaizer Chiefs | - | Chippa United | 4:0 | ||||
| 8. Journée | 24.10.2021 | SuperSport United | - | Kaizer Chiefs | 1:2 | ||||
| 12. Journée | 28.11.2021 | Moroka Swallows | - | Kaizer Chiefs | 1:3 | ||||
| 15. Journée | 12.12.2021 | Kaizer Chiefs | - | Sekhukhune United | 2:0 | ||||
| 16. Journée | 19.12.2021 | Royal AM | - | Kaizer Chiefs | 1:0 | ||||
| 18. Journée | 15.02.2022 | Cape Town City FC | - | Kaizer Chiefs | 0:0 | ||||
| 20. Journée | 26.02.2022 | Baroka FC | - | Kaizer Chiefs | 0:1 | ||||
| 21. Journée | 05.03.2022 | Orlando Pirates | - | Kaizer Chiefs | 1:2 | ||||
| 22. Journée | 19.03.2022 | Kaizer Chiefs | - | Golden Arrows | 0:1 | ||||
| 23. Journée | 02.04.2022 | Chippa United | - | Kaizer Chiefs | 1:3 | ||||
| 24. Journée | 05.04.2022 | Kaizer Chiefs | - | TS Galaxy | 0:0 | ||||
| 29. Journée | 14.05.2022 | Sekhukhune United | - | Kaizer Chiefs | 0:1 | ||||
| 30. Journée | 21.05.2022 | Kaizer Chiefs | - | Moroka Swallows | 2:2 |
Afrique du Sud