| 1. Journée | 28.08.2005 | Reggina Calcio | - | AS Roma | 0:3 |  |
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| 2. Journée | 11.09.2005 | AS Roma | - | Udinese Calcio | 0:1 | ||||
| 3. Journée | 18.09.2005 | AS Livorno | - | AS Roma | 0:0 | ||||
| 4. Journée | 21.09.2005 | AS Roma | - | Parma FC | 4:1 | |
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| 5. Journée | 25.09.2005 | Cagliari Calcio | - | AS Roma | 0:0 | ||||
| 6. Journée | 02.10.2005 | AS Roma | - | AC Siena | 2:3 | ||||
| 7. Journée | 16.10.2005 | Empoli FC | - | AS Roma | 1:0 | ||||
| 8. Journée | 23.10.2005 | AS Roma | - | Lazio Roma | 1:1 | ||||
| 9. Journée | 26.10.2005 | Inter | - | AS Roma | 2:3 | ||||
| 10. Journée | 30.10.2005 | AS Roma | - | Ascoli Calcio | 2:1 | ||||
| 11. Journée | 06.11.2005 | FC Messina | - | AS Roma | 0:2 | ||||
| 12. Journée | 19.11.2005 | AS Roma | - | Juventus | 1:4 | ||||
| 14. Journée | 04.12.2005 | US Lecce | - | AS Roma | 2:2 | |
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| 15. Journée | 11.12.2005 | AS Roma | - | US Palermo | 1:2 | ||||
| 37. Journée | 07.05.2006 | AS Roma | - | Treviso FBC | 1:0 | ||||
| 38. Journée | 14.05.2006 | AC Milan | - | AS Roma | 2:1 |
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